YRC Public Data Repository - Protein Structure Prediction

Protein:	SEC62
Organism:	Homo sapiens
Length:	399 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC62.

Description	E-value	Query Range	Subject Range
SEC62_PONAB - Translocation protein SEC62 OS=Pongo abelii GN=SEC62 PE=2 SV=1 SEC62_PONPY - Translocation protein SEC62 - Pongo pygmaeus (Orangutan)	0.0	[1..399]	[1..399]
gi\|33086592, gi\|... - gi\|77735350\|ref\|NP_001029301.1\| SEC62 homolog [Rattus norvegicus], gi\|33086592\|gb\|AAP92608.1\| Ab2-29...	0.0	[1..399]	[208..605]
gi\|109044382 - gi\|109044382\|ref\|XP_001090325.1\| PREDICTED: similar to translocation protein 1 [Macaca mulatta]	0.0	[1..399]	[1..399]
SEC62_MOUSE - Translocation protein SEC62 OS=Mus musculus GN=Sec62 PE=1 SV=1	0.0	[1..399]	[1..398]
gi\|76607701, gi\|... - gi\|76607701\|ref\|XP_878152.1\| PREDICTED: similar to translocation protein 1 isoform 3 [Bos taurus], g...	0.0	[1..399]	[1..399]
gi\|74003737 - gi\|74003737\|ref\|XP_851757.1\| PREDICTED: similar to translocation protein 1 [Canis familiaris]	0.0	[1..399]	[75..473]
SEC62_CHICK - Translocation protein SEC62 OS=Gallus gallus GN=SEC62 PE=2 SV=1	0.0	[1..399]	[1..398]
gi\|114590309 - gi\|114590309\|ref\|XP_001162758.1\| PREDICTED: similar to translocation protein-1 isoform 1 [Pan troglo... gi\|119598935, gi... - gi\|119598935\|gb\|EAW78529.1\| translocation protein 1, isoform CRA_b [Homo sapiens], gi\|119598934\|gb\|E...	0.0	[39..399]	[1..361]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAERRRHKKR IQEVGEPSKE EKAVAKYLRF NCPTKSTNMM GHRVDYFIAS KAVDCLLDSK  60
   61 WAKAKKGEEA LFTTRESVVD YCNRLLKKQF FHRALKVMKM KYDK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [105-291]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIKKEKDKGK AESGKEEDKK SKKENIKDEK TKKEKEKKKD GEKEESKKEE TPGTPKKKET  60
   61 KKKFKLEPHD DQVFLDGNEV YVWIYDPVHF KTFVMGLILV IAVIAATLFP LWPAEMRVGV 120
  121 YYLSVGAGCF VASILLLAVA RCILFLIIWL ITGGRHHFWF LPNLTADVGF IDSFRPLYTH 180
  181 EYKGPKA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.08
Match:	2h8aA
Description:	No description for 2h8aA was found.

Predicted Domain #3

Region A:
Residues: [292-399]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLKKDEKSET KKQQKSDSEE KSDSEKKEDE EGKVGPGNHG TEGSGGERHS DTDSDRREDD  60
   61 RSQHSSGNGN DFEMITKEEL EQQTDGDCEE DEEEENDGET PKSSHEKS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.39
Match:	1qd7B
Description:	30S subunit
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits