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View Structure Prediction Details

Protein: INA
Organism: Homo sapiens
Length: 499 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INA.

Description E-value Query
Range
Subject
Range
gi|109096771 - gi|109096771|ref|XP_001093676.1| PREDICTED: keratin, hair, basic, 4 [Macaca mulatta]
251.0 [0..2] [409..49]
gi|109481333 - gi|109481333|ref|XP_001064779.1| PREDICTED: similar to keratin Kb40 [Rattus norvegicus]
250.0 [0..3] [420..160]
gi|73996557 - gi|73996557|ref|XP_850166.1| PREDICTED: similar to keratin, hair, basic, 3 [Canis familiaris]
248.0 [0..3] [409..103]
gi|42760016 - gi|42760016|emb|CAF31524.1| type II hair keratin 4 [Homo sapiens]
245.0 [0..2] [409..47]
gi|114644580 - gi|114644580|ref|XP_522389.2| PREDICTED: keratin, hair, basic, 4 [Pan troglodytes]
242.0 [0..2] [409..49]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFGSEHYLC SSSSYRKVFG DGSRLSARLS GAGGAGGFRS QSLSRSNVAS SAACSSASSL  60
   61 GLGLAYRR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 8.677781
Match: PF04732.5
Description: No description for PF04732.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPASDGLDLS QAAARTNEYK IIRTNEKEQL QGLNDRFAVF IEKVHQLETQ NRALEAELAA  60
   61 LRQRHAEPSR VGELFQRELR DLRAQLEEAS SARSQALLER DGLAEEVQRL RARCEEESRG 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [189-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REGAERALKA QQRDVDGATL ARLDLEKKVE SLLDELAFVR QVHDEEVAEL LATLQASSQA  60
   61 AAEVDVTVAK PDLTSALREI RAQYESLAAK NLQSAEEWYK SKFANLNEQA ARSTEAIRAS 120
  121 REEIHEYRRQ 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.14
Match: 1fxkC
Description: Prefoldin alpha subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [319-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQARTIEIEG LRGANESLER QILELEERHS AEVAGYQDSI GQLENDLRNT KSEMARHLRE  60
   61 YQDLLNVKMA LDIEIAAYRK LLEGEETRFS T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 1gk4A
Description: Vimentin coil
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [410-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGLSISGLNP LPNPSYLLPP RILSATTSKV SSTGLSLKKE EEEEEASKVA SKKTSQIGES  60
   61 FEEILEETVI STKKTEKSNI EETTISSQKI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle