YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|119590655, gi...
Organism: Homo sapiens
Length: 522 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119590655, gi....

Description E-value Query
Range
Subject
Range
gi|4731239 - gi|4731239|gb|AAD28403.1|AF111345_1 caspase-10/d [Homo sapiens]
0.0 [1..522] [1..522]
gi|197101089 - gi|197101089|ref|NP_001127368.1| caspase 10, apoptosis-related cysteine peptidase [Pongo abelii]
gi|55728617 - gi|55728617|emb|CAH91049.1| hypothetical protein [Pongo abelii]
0.0 [1..522] [1..523]
gi|109100559 - gi|109100559|ref|XP_001097804.1| PREDICTED: similar to caspase 10 isoform d preproprotein isoform 3 ...
0.0 [1..522] [1..520]
gi|114582609 - gi|114582609|ref|XP_001172193.1| PREDICTED: caspase 8 isoform 12 [Pan troglodytes]
0.0 [17..514] [59..536]

Back

Predicted Domain #1
Region A:
Residues: [1-266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSQGQHWYS SSDKNCKVSF REKLLIIDSN LGVQDVENLK FLCIGLVPNK KLEKSSSASD  60
   61 VFEHLLAEDL LSEEDPFFLA ELLYIIRQKK LLQHLNCTKE EVERLLPTRQ RVSLFRNLLY 120
  121 ELSEGIDSEN LKDMIFLLKD SLPKTEMTSL SFLAFLEKQG KIDEDNLTCL EDLCKTVVPK 180
  181 LLRNIEKYKR EKAIQIVTPP VDKEAESYQG EEELVSQTDV KTFLEALPQE SWQNKHAGSN 240
  241 GNRATNGAPS LVSRGMQGAS ANTLNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2bbzA
Description: Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [267-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETSTKRAAVY RMNRNHRGLC VIVNNHSFTS LKDRQGTHKD AEILSHVFQW LGFTVHIHNN  60
   61 VTKVEMEMVL QKQKCNPAHA DGDCFVFCIL THGRFGAVYS SDEALIPIRE IMSHFTALQC 120
  121 PRLAEKPKLF FIQACQGEEI QPSVSIEADA LNPEQAPTSL QDSIPAEADF LLGLATVPGY 180
  181 VSFRHVEEGS WYIQSLCNHL KKLVPRHEDI LSILTAVNDD VSRRVDKQGT KKQMPQPAFT 240
  241 LRKKLVFPVP LDALSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.0
Match: 1i4eB
Description: Caspase-8
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle