YRC Public Data Repository - Protein Structure Prediction

Protein:	PRLH
Organism:	Homo sapiens
Length:	87 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRLH.

Description	E-value	Query Range	Subject Range
PRRP_SHEEP - Prolactin-releasing peptide OS=Ovis aries GN=PRLH PE=2 SV=1	7.0E-24	[23..85]	[23..85]
gi\|109101599 - gi\|109101599\|ref\|XP_001084860.1\| PREDICTED: similar to prolactin releasing hormone [Macaca mulatta]	8.0E-24	[1..87]	[1..85]
gi\|82881160, gi\|... - gi\|94365377\|ref\|XP_985109.1\| PREDICTED: similar to prolactin releasing hormone [Mus musculus], gi\|82...	2.0E-23	[5..85]	[4..84]
PRRP_RAT - Prolactin-releasing peptide OS=Rattus norvegicus GN=Prlh PE=2 SV=1	1.0E-22	[19..87]	[18..83]
PRRP_BOVIN - Prolactin-releasing peptide OS=Bos taurus GN=PRLH PE=1 SV=1	3.0E-21	[23..85]	[23..85]
gi\|4587205 - gi\|4587205\|dbj\|BAA76662.1\| C-RF amide precursor [Carassius auratus]	4.0E-20	[8..64]	[24..86]
gi\|73994200 - gi\|73994200\|ref\|XP_848794.1\| PREDICTED: similar to prolactin releasing hormone [Canis familiaris]	1.0E-19	[19..87]	[19..87]
gi\|87242615 - gi\|87242615\|gb\|ABD33839.1\| prolactin-releasing peptide C-RFamide precursor [Cyprinus carpio]	1.0E-17	[8..64]	[24..84]
gi\|112821186 - gi\|112821186\|dbj\|BAF03223.1\| prolactin-releasing peptide [Xenopus laevis]	7.0E-13	[9..69]	[24..84]
gi\|66269758, gi\|... - gi\|66269758\|gb\|AAY43233.1\| prolactin-releasing peptide C-RFamide precursor [Salmo salar], gi\|1851321...	2.0E-11	[22..57]	[69..110]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLRAWLLC LLMLGLALRG AASRTHRHSM EIRTPDINPA WYASRGIRPV GRFGRRRATL  60
   61 GDVPKPGLRP RLTCFPLEGG AMSSQDG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.356	d.58.24	CheY-binding domain of CheA
View	Download	0.292	a.4.1	Homeodomain-like
View	Download	0.277	a.35.1	lambda repressor-like DNA-binding domains
View	Download	0.244	a.6.1	Putative DNA-binding domain
View	Download	0.223	a.5.1	DNA helicase RuvA subunit, C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits