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View Structure Prediction Details

Protein: LZIC
Organism: Homo sapiens
Length: 190 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LZIC.

Description E-value Query
Range
Subject
Range
gi|74268135 - gi|74268135|gb|AAI03025.1| LZIC protein [Bos taurus]
5.0E-70 [4..190] [1..187]
gi|114553860 - gi|114553860|ref|XP_001161117.1| PREDICTED: leucine zipper and CTNNBIP1 domain containing isoform 2 ...
1.0E-69 [1..172] [1..172]
LZIC_RAT - Protein LZIC OS=Rattus norvegicus GN=Lzic PE=2 SV=1
2.0E-69 [1..190] [1..190]
gi|57113193 - gi|57113193|ref|XP_548561.1| PREDICTED: similar to leucine zipper and CTNNBIP1 domain containing [Ca...
4.0E-69 [1..190] [1..190]
LZIC_MOUSE - Protein LZIC OS=Mus musculus GN=Lzic PE=1 SV=1
6.0E-67 [1..190] [1..190]
LZIC_CHICK - Protein LZIC OS=Gallus gallus GN=LZIC PE=2 SV=1
4.0E-65 [1..190] [1..190]
LZIC_XENTR - Protein LZIC OS=Xenopus tropicalis GN=lzic PE=2 SV=1
2.0E-63 [1..190] [1..190]
gi|108996632, gi... - gi|108996635|ref|XP_001100273.1| PREDICTED: similar to leucine zipper and CTNNBIP1 domain containing...
2.0E-58 [1..190] [1..183]
gi|47228808 - gi|47228808|emb|CAG07540.1| unnamed protein product [Tetraodon nigroviridis]
3.0E-55 [1..186] [1..186]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRGKTETS KLKQNLEEQL DRLMQQLQDL EECREELDTD EYEETKKETL EQLSEFNDSL  60
   61 KKIMSGNMTL VDELSGMQLA IQAAISQAFK TPEVIRLFAK KQPGQLRTRL AEM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.957 0.072 beta-catenin binding a.47.2 t-snare proteins

Predicted Domain #2
Region A:
Residues: [114-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRDLMVGKLE RDLYTQQKVE ILTALRKLGE KLTADDEAFL SANAGAILSQ FEKVSTDLGS  60
   61 GDKILALASF EVEKTKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.39794
Match: 1m1eB
Description: beta-catenin-interacting protein ICAT
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle