YRC Public Data Repository - Protein Structure Prediction

Protein:	YWHAE
Organism:	Homo sapiens
Length:	255 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YWHAE.

Description	E-value	Query Range	Subject Range
gi\|109087133 - gi\|109087133\|ref\|XP_001098275.1\| PREDICTED: similar to tyrosine 3/tryptophan 5 -monooxygenase activa...	0.0	[3..244]	[335..574]
gi\|68436321 - gi\|68436321\|ref\|XP_699659.1\| PREDICTED: similar to tyrosine 3-monooxygenase/tryptophan 5-monooxygena...	0.0	[3..244]	[1533..1772]
gi\|60654187, gi\|... - gi\|61371807\|gb\|AAX43735.1\| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein ep...	0.0	[1..255]	[1..255]
gi\|31981925, gi\|... - gi\|31981925\|ref\|NP_033562.2\| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein,...	0.0	[1..255]	[1..255]
gi\|114665589 - gi\|114665589\|ref\|XP_001154015.1\| PREDICTED: similar to epsilon isoform of 14-3-3 protein isoform 5 [...	0.0	[1..255]	[1..256]
gi\|2895518, gi\|2... - gi\|2895518\|gb\|AAC41251.1\| 14-3-3 protein epsilon [Xenopus laevis], gi\|27924430\|gb\|AAH45025.1\| Ywhae-...	0.0	[1..255]	[1..255]
gi\|56118781, gi\|... - gi\|89271261\|emb\|CAJ83225.1\| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, ...	0.0	[1..255]	[1..255]
gi\|13928824, gi\|... - gi\|1469948\|gb\|AAC52676.1\| 14-3-3 protein epsilon isoform, gi\|13928824\|ref\|NP_113791.1\| tyrosine 3-mo...	0.0	[1..255]	[1..255]

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Predicted Domain #1

Region A:
Residues: [1-255]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK NVIGARRASW  60
   61 RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI LDVLDKHLIP AANTGESKVF 120
  121 YYKMKGDYHR YLAEFATGND RKEAAENSLV AYKAASDIAM TELPPTHPIR LGLALNFSVF 180
  181 YYEILNSPDR ACRLAKAAFD DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE 240
  241 EQNKEALQDV EDENQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.0
Match:	2br9A
Description:	14-3-3 Protein Epsilon (Human) Complexed to Peptide
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits