YRC Public Data Repository - Protein Structure Prediction

Protein:	ACTL6A
Organism:	Homo sapiens
Length:	429 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACTL6A.

Description	E-value	Query Range	Subject Range
gi\|109489498 - gi\|109489498\|ref\|XP_001076100.1\| PREDICTED: similar to Actin, cytoplasmic 2 (Gamma-actin) [Rattus no...	0.0	[4..428]	[307..683]
gi\|45269029 - gi\|45269029\|gb\|AAS55927.1\| cytoskeletal beta actin [Sus scrofa]	0.0	[8..428]	[31..403]
gi\|18565104 - gi\|18565104\|dbj\|BAB84579.1\| Actin 2 [Crassostrea gigas]	0.0	[7..428]	[2..375]
gi\|223855 - gi\|223855\|prf\|\|1002250A actin	0.0	[8..428]	[1..373]
gi\|224305 - gi\|224305\|prf\|\|1101351B actin	0.0	[8..428]	[1..373]
gi\|109729854 - gi\|109729854\|gb\|ABG46341.1\| actin [Aedes albopictus]	0.0	[8..428]	[3..375]
gi\|29293659 - gi\|29293659\|gb\|AAO67718.1\| beta actin [Engystomops pustulosus]	0.0	[8..428]	[4..376]
gi\|66549344, gi\|... - gi\|66549344\|ref\|XP_623381.1\| PREDICTED: similar to Actin-5C isoform 2 [Apis mellifera], gi\|48137684\|...	0.0	[7..428]	[2..375]

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Predicted Domain #1

Region A:
Residues: [1-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGVYGGDE VGALVFDIGS YTVRAGYAGE DCPKVDFPTA IGMVVERDDG STLMEIDGDK  60
   61 GKQGGPTYYI DTNALRVPRE NMEAISPLKN GMVEDWDSFQ AILDHTYKMH VKSEASLHPV 120
  121 LMSEAPWNTR AKREKLTELM FEHYNIPAFF LCKTAVLTAF ANGRSTGLIL DSGATHTTAI 180
  181 PVHDGYVLQQ GIVKSPLAGD FITMQCRELF QEMNIELVPP YMIASKEAVR EGSPANWKRK 240
  241 EKLPQVTRSW HNYMCNCVIQ DFQASVLQVS DSTYDEQVAA QMPTVHYEFP NGYNCDFGAE 300
  301 RLKIPEGLFD PSNVKGLSGN TMLGVSHVVT TSVGMCDIDI RPGLYGSVIV AGGNTLIQSF 360
  361 TDRLNRELSQ KTPPSMRLKL IANNTTVERR FSSWIGGSIL ASLGTFQQMW ISKQEYEEGG 420
  421 KQCVERKCP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	153.0
Match:	1hluA
Description:	Actin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits