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View Structure Prediction Details

Protein: SFPQ
Organism: Homo sapiens
Length: 707 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SFPQ.

Description E-value Query
Range
Subject
Range
gi|73976787 - gi|73976787|ref|XP_857499.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
2.0E-81 [293..707] [7..422]
gi|76689285 - gi|76689285|ref|XP_881509.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
2.0E-80 [293..707] [7..422]
gi|125602953, gi... - gi|34015145|gb|AAQ56342.1| putative poly(A)-binding protein [Oryza sativa (japonica cultivar-group)]...
gi|125561054 - gi|125561054|gb|EAZ06502.1| hypothetical protein OsI_28747 [Oryza sativa Indica Group]
3.0E-79 [294..700] [36..436]
gi|82934590 - gi|82934590|ref|XP_906031.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
8.0E-76 [293..707] [7..422]

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Predicted Domain #1
Region A:
Residues: [1-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRDRFRSRG GGGGGFHRRG GGGGRGGLHD FRSPPPGMGL NQNRGPMGPG PGQSGPKPPI  60
   61 PPPPPHQQQQ QPPPQQPPPQ QPPPHQPPPH PQPHQQQQPP PPPQDSSKPV VAQGPGPAPG 120
  121 VGSAPPASSS APPATPPTSG APPGSGPGPT PTPPPAVTSA PPGAPPPTPP SSGVPTTPPQ 180
  181 AGGPPPPPAA VPGPGPGPKQ GPGPG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [206-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPKGGKMPGG PKPGGGPGLS TPGGHPKPPH RGGGEPRGGR QHHPPYHQQH HQGPPPGGPG  60
   61 GRSEEKISDS EGFKANLSLL RRPG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1wckA
Description: Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [290-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKTYTQRCRL FVGNLPADIT EDEFKRLFAK YGEPGEVFIN KGKGFGFIKL ESRALAEIAK  60
   61 AELDDTPMRG RQLRVRFATH A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 2cpjA
Description: Solution structure of the N-terminal RNA recognition motif of NonO
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [371-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AALSVRNLSP YVSNELLEEA FSQFGPIERA VVIVDDRGRS TGKGIVEFAS KPAARKAFER  60
   61 CSEGVFLLTT TPRPVIVEPL EQLDDEDGLP EKLAQKNPMY QKERETPPRF AQHGTFEYEY 120
  121 SQRWKSLDEM EKQQREQVEK NMKDAKDKLE SEMEDAYHEH QANLLRQDLM RRQEELRRME 180
  181 EL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.06
Match: 1fnxH
Description: Hu antigen C (Huc)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.787118623292657 bayes_pls_golite062009
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [553-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNQEMQKRKE MQLRQEEERR RREEEMMIRQ REMEEQMRRQ REESYSRMGY MDPRERDMRM  60
   61 GGGGAMNMGD PYGSGGQKFP PLGGGGGIGY EANPGVPPAT MSGSMMGSDM RTERFGQGGA 120
  121 GPVGGQGPRG MGPGTPAGYG RGREEYEGPN KKPRF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 2d9pA
Description: No description for 2d9pA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle