YRC Public Data Repository - Protein Structure Prediction

Protein:	HNRPH3
Organism:	Homo sapiens
Length:	346 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HNRPH3.

Description	E-value	Query Range	Subject Range
gi\|76633747 - gi\|76633747\|ref\|XP_881817.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	3.0E-45	[1..295]	[1..293]
gi\|73976777 - gi\|73976777\|ref\|XP_857296.1\| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...	8.0E-45	[1..305]	[1..303]
gi\|13560783 - gi\|13560783\|gb\|AAK30205.1\|AF349964_1 poly(A)-binding protein [Daucus carota]	1.0E-44	[4..345]	[116..481]
PABP8_ARATH - Polyadenylate-binding protein 8 OS=Arabidopsis thaliana GN=PAB8 PE=1 SV=1	1.0E-44	[4..345]	[121..485]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGLE IVPNGITLTM DYQGRSTGEA  60
   61 FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY DPPRRLLGQR P

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.69897
Match:	1wg5A
Description:	Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.950788308762215	bayes_pls_golite062009
nucleic acid binding	0.29562225149076	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [112-346]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPYDRPIGGR GGYYGAGRGS MYDRMRRGGD GYDGGYGGFD DYGGYNNYGY GNDGFDDRMR  60
   61 DGRGMGGHGY GGAGDASSGF HGGHFVHMRG LPFRATENDI ANFFSPLNPI RVHIDIGADG 120
  121 RATGEADVEF VTHEDAVAAM SKDKNNMQHR YIELFLNSTP GGGSGMGGSG MGGYGRDGMD 180
  181 NQGGYGSVGR MGMGNNYSGG YGTPDGLGGY GRGGGGSGGY YGQGGMSGGG WRGMY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	2hgnA
Description:	No description for 2hgnA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: