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View Structure Prediction Details

Protein: LEO1
Organism: Homo sapiens
Length: 666 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEO1.

Description E-value Query
Range
Subject
Range
LEO1_PONPY - RNA polymerase-associated protein LEO1 - Pongo pygmaeus (Orangutan)
LEO1_PONAB - RNA polymerase-associated protein LEO1 OS=Pongo abelii GN=LEO1 PE=2 SV=1
3.0E-73 [1..658] [1..658]
LEO1_MOUSE - RNA polymerase-associated protein LEO1 OS=Mus musculus GN=Leo1 PE=1 SV=2
6.0E-72 [1..658] [1..659]
gi|76625547 - gi|76625547|ref|XP_870169.1| PREDICTED: similar to Leo1, Paf1/RNA polymerase II complex component, h...
5.0E-71 [1..658] [1..660]
gi|74000154 - gi|74000154|ref|XP_535485.2| PREDICTED: similar to senescence downregulated leo1-like isoform 2 [Can...
2.0E-70 [1..658] [1..657]
LEO1_RAT - RNA polymerase-associated protein LEO1 OS=Rattus norvegicus GN=Leo1 PE=1 SV=1
9.0E-67 [1..658] [1..670]
gi|50752937 - gi|50752937|ref|XP_413803.1| PREDICTED: similar to senescence downregulated leo1-like [Gallus gallus...
4.0E-60 [1..658] [1..649]
LEO1_XENLA - RNA polymerase-associated protein LEO1 OS=Xenopus laevis GN=leo1 PE=2 SV=1
3.0E-44 [25..658] [57..694]
LEO1_DANRE - RNA polymerase-associated protein LEO1 OS=Danio rerio GN=leo1 PE=1 SV=1
1.0E-43 [1..658] [1..639]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADMEDLFGS DADSEAERKD SDSGSDSDSD QENAASGSNA SGSESDQDER GDSGQPSNKE  60
   61 LFGDDSEDEG ASHHSGSDNH SERSDNRSEA SERSDHEDND PSDVDQHSGS EAPNDDEDEG 120
  121 HRSDGGSHHS EAEGSEKAHS DDEKWGREDK SDQSDDEKIQ NSDDEERAQG SDEDKLQNSD 180
  181 DDEKMQNTDD EERPQLSDDE R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [202-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQLSEEEKAN SDDERPVASD NDDEKQNSDD EEQPQLSDEE KMQNSDDERP QASDEEHRHS  60
   61 DDEEEQDHKS ESARGSDSED EVLRMKRKNA IASDSEADSD TEVPKDNSGT MDLFGGADDI 120
  121 SSGSDGEDKP PTPGQPVDEN GLPQDQQEEE PIPETRIEVE IPKVNTDLGN DLYFVKLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [380-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFLSVEPRPF DPQYYEDEFE DEEMLDEEGR TRLKLKVENT IRWRIRRDEE GNEIKESNAR  60
   61 IVKWSDGSMS LHLGNEVFDV YKAPLQGDHN HLFIRQGTGL QGQAVFKTKL TFRPHSTDSA 120
  121 THRKMTLSLA DRCSKTQKIR ILPMAGRDPE CQRTEMIKKE EERLRASIRR ESQQRRMREK 180
  181 QH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [562-666]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRGLSASYLE PDRYDEEEEG EESISLAAIK NRYKGGIREE RARIYSSDSD EGSEEDKAQR  60
   61 LLKAKKLTSD EEGEPSGKRK AEDDDKANKK HKKYVISDEE EEDDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle