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View Structure Prediction Details

Protein: ERAL1
Organism: Homo sapiens
Length: 437 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERAL1.

Description E-value Query
Range
Subject
Range
ERAL1_MOUSE - GTPase Era, mitochondrial OS=Mus musculus GN=Eral1 PE=2 SV=1
8.0E-68 [1..437] [1..437]
gi|114668384 - gi|114668384|ref|XP_511365.2| PREDICTED: Era G-protein-like 1 [Pan troglodytes]
2.0E-65 [1..437] [66..502]
gi|14211570 - gi|14211570|dbj|BAB56112.1| conserved ERA-like GTPase [Homo sapiens]
3.0E-65 [1..437] [1..437]
gi|61557359, gi|... - gi|61557359|ref|NP_001013247.1| Era-like 1 [Rattus norvegicus], gi|59808216|gb|AAH89885.1| Era (G-pr...
1.0E-62 [1..437] [1..431]
gi|109113889 - gi|109113889|ref|XP_001107234.1| PREDICTED: similar to Era G-protein-like 1 [Macaca mulatta]
6.0E-62 [1..437] [81..517]
gi|76643289 - gi|76643289|ref|XP_874154.1| PREDICTED: similar to Era G-protein-like 1 isoform 2 [Bos taurus]
2.0E-56 [1..437] [1..431]

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Predicted Domain #1
Region A:
Residues: [1-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPSWRGAR LVQSVLRVWQ VGPHVARERV IPFSSLLGFQ RRCVSCVAGS AFSGPRLASA  60
   61 SRSNGQGSAL DHFLGFSQPD SSVTPCVPAV SMNRDEQDVL LVHHPDMPEN SRVLRVVLLG 120
  121 APNAGKSTLS NQLLGRKVFP VSRKVHTTRC QALGVITEKE TQVILLDTPG IISPGKQKRH 180
  181 HLELSLLEDP WKSMESADLV VVLVDVSDKW TRNQLSPQLL RCLTKYSQIP SVLVMNKVDC 240
  241 LKQKSVLLEL TAALTEGVVN GKKLKMRQAF HSHPGTHCPS PAVKDPNTQS VGNPQRIGWP 300
  301 HFKEIFMLSA LSQEDVKTLK QYLLTQAQPG PWEYHSAVLT SQTPEEICAN IIREKLLEHL 360
  361 PQEVPYN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 2hjgA
Description: No description for 2hjgA was found.

Predicted Domain #2
Region A:
Residues: [368-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQQKTAVWEE GPGGELVIQQ KLLVPKESYV KLLIGPKGHV ISQIAQEAGH DLMDIFLCDV  60
   61 DIRLSVKLLK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1egaA
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle