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View Structure Prediction Details

Protein: CLU
Organism: Homo sapiens
Length: 449 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLU.

Description E-value Query
Range
Subject
Range
gi|61355191 - gi|61355191|gb|AAX41112.1| clusterin [synthetic construct]
0.0 [1..449] [1..449]
gi|114619438 - gi|114619438|ref|XP_001164607.1| PREDICTED: clusterin isoform 13 [Pan troglodytes]
0.0 [1..449] [69..517]
gi|42716297 - gi|42716297|ref|NP_001822.2| clusterin isoform 1 [Homo sapiens]
0.0 [1..449] [53..501]
gi|546505, gi|21... - gi|546505|gb|AAB30623.1| apolipoprotein J; apoJ [Mus sp.], gi|2119394|pir||I56335 apolipoprotein J -...
0.0 [2..449] [1..448]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKTLLLFVG LLLTWESGQV LGDQTVSDNE LQEMSNQGSK YVNKEIQNAV NGVKQIKTLI  60
   61 EKTNEERKTL LSNLEEA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.398 N/A N/A a.140.1 LEM domain
View Download 0.345 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.339 N/A N/A a.4.1 Homeodomain-like
View Download 0.335 N/A N/A a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.335 N/A N/A a.153.1 Nuclear receptor coactivator interlocking domain

Predicted Domain #2
Region A:
Residues: [78-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKKEDALNE TRESETKLKE LPGVCNETMM ALWEECKPCL KQTCMKFYAR VCRSGSGLVG  60
   61 RQLEEFLNQS SPFYFWMNGD RIDSLLENDR QQTHMLDVMQ DHFSRASSII DELFQDRFFT 120
  121 REPQDTYHYL PFSLPHRRPH FFFPKSRIVR SLMPFSPYEP LNFHAMFQPF LEMIHEAQQA 180
  181 MDIHFHSPAF QHPPTEF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [275-449]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IREGDDDRTV CREIRHNSTG CLRMKDQCDK CREILSVDCS TNNPSQAKLR RELDESLQVA  60
   61 ERLTRKYNEL LKSYQWKMLN TSSLLEQLNE QFNWVSRLAN LTQGEDQYYL RVTTVASHTS 120
  121 DSDVPSGVTE VVVKLFDSDP ITVTVPVEVS RKNPKFMETV AEKALQEYRK KHREE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.570 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.522 N/A N/A a.25.1 Ferritin-like
View Download 0.421 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.413 N/A N/A c.47.1 Thioredoxin-like
View Download 0.386 N/A N/A d.110.4 SNARE-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle