YRC Public Data Repository - Protein Structure Prediction

Protein:	MAPKAP1
Organism:	Homo sapiens
Length:	522 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAPKAP1.

Description	E-value	Query Range	Subject Range
gi\|48762796 - gi\|48762796\|gb\|AAT46479.1\| mitogen-activated protein kinase 2-associated protein 1b [Homo sapiens]	895.0	[0..1]	[522..1]
gi\|55726571 - gi\|55726571\|emb\|CAH90052.1\| hypothetical protein [Pongo abelii] SIN1_PONAB - Target of rapamycin complex 2 subunit MAPKAP1 OS=Pongo abelii GN=MAPKAP1 PE=2 SV=1	894.0	[0..1]	[522..1]
SIN1_RAT - Target of rapamycin complex 2 subunit MAPKAP1 OS=Rattus norvegicus GN=Mapkap1 PE=2 SV=1	893.0	[0..1]	[522..1]
SIN1_MOUSE - Target of rapamycin complex 2 subunit MAPKAP1 OS=Mus musculus GN=Mapkap1 PE=1 SV=1	892.0	[0..1]	[522..1]
gi\|73968037 - gi\|73968037\|ref\|XP_537845.2\| PREDICTED: similar to Stress-activated map kinase interacting protein 1...	890.0	[0..1]	[522..1]
SIN1_SHEEP - Target of rapamycin complex 2 subunit MAPKAP1 OS=Ovis aries GN=MAPKAP1 PE=1 SV=1	883.0	[0..1]	[522..1]
SIN1_CHICK - Target of rapamycin complex 2 subunit MAPKAP1 OS=Gallus gallus GN=MAPKAP1 PE=2 SV=1	860.0	[0..1]	[522..1]
SIN1_XENLA - Target of rapamycin complex 2 subunit MAPKAP1 OS=Xenopus laevis GN=mapkap1 PE=2 SV=1	838.0	[0..1]	[520..1]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFLDNPTII LAHIRQSHVT SDDTGMCEMV LIDHDVDLEK IHPPSMPGDS GSEIQGSNGE  60
   61 TQGYVYAQSV DITSSWDFGI RRRSNTAQRL ERLRKERQNQ IKCKNIQWKE RNSKQSAQEL 120
  121 KSLFEKKSLK EKPPISGKQS ILSVRLEQCP LQLNNPFNEY SKFDGKGHVG TTATKKIDVY 180
  181 LPLHSSQDRL LPMTVVTMAS ARVQDLIGLI CWQYTSEG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [219-257]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REPKLNDNVS AYCLHIAEDD GEVDTDFPPL DSNEPIHKF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [258-359]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFSTLALVEK YSSPGLTSKE SLFVRINAAH GFSLIQVDNT KVTMKEILLK AVKRRKGSQK  60
   61 VSGPQYRLEK QSEPNVAVDL DSTLESQSAW EFCLVRENSS RA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [360-419]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGVFEEDSQI DIATVQDMLS SHHYKSFKVS MIHRLRFTTD VQLGISGDKV EIDPVTNQKA  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.814	b.34.5	Translation proteins SH3-like domain

Predicted Domain #5

Region A:
Residues: [420-522]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STKFWIKQKP ISIDSDLLCA CDLAEEKSPS HAIFKLTYLS NHDYKHLYFE SDAATVNEIV  60
   61 LKVNYILESR ASTARADYFA QKQRKLNRRT SFSFQKEKKS GQQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.828	d.129.2	Phosphoglucomutase, C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits