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View Structure Prediction Details

Protein: gi|18203725, gi|...
Organism: Homo sapiens
Length: 653 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|18203725, gi|....

Description E-value Query
Range
Subject
Range
gi|114609535 - gi|114609535|ref|XP_001171863.1| PREDICTED: RALBP1 associated Eps domain containing 1 isoform 4 [Pan...
0.0 [1..653] [53..705]
gi|76671760, gi|... - gi|76671760|ref|XP_881123.1| PREDICTED: similar to RalBP1 associated Eps domain containing protein 1...
1.0E-98 [1..653] [53..704]
gi|109072569 - gi|109072569|ref|XP_001094285.1| PREDICTED: RALBP1 associated Eps domain containing 1 isoform 3 [Mac...
8.0E-96 [1..653] [53..706]
gi|73945607 - gi|73945607|ref|XP_860731.1| PREDICTED: similar to RalBP1 associated Eps domain containing protein 1...
2.0E-95 [1..653] [1..653]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELCGATRLG YFGRSQFYIA LKLVAVAQSG FPLRVESINT VKDLPLPRFV ASKNEQESRH  60
   61 AASYSSDSEN QGSYSGVIPP PPGRGQVKKG SVSHDTVQPR TSADAQEPAS PVVSPQQSPP 120
  121 TSPHTWRKH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 1pk8A
Description: Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [130-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRHPSGGNSE RPLAGPGPFW SPFGEAQSGS SAGDAVWSGH SPPPPQENWV SFADTPPTST  60
   61 LLTMHPASVQ DQTTVRTVAS ATTAIEIRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [219-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSSYDDPWK ITDEQRQYYV NQFKTIQPDL NGFIPGSAAK EFFTKSKLPI LELSHIWELS  60
   61 DFDKDGALTL DEFCAAFHLV VARKNGYDLP EKLPESLMPK LIDLEDSADV G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.39794
Match: 1fi6A
Description: Reps1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [330-395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQPGEVGYSG SPAEAPPSKS PSMPSLNQTW PELNQSSEDT AIVHPVPIRM TPSKIHMQEM  60
   61 ELKRTG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [396-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDHTNPTSPL LVKPSDLLEE NKINSSVKFA SGNTVGQQQA GVVAHPPAVP PRPQPSQAPG  60
   61 PAVHRPVDAD GLITHTSTSP QQIPEQPNFA DFSQFEVFAA SNVNDEQDDE AEKHPEVLPA 120
  121 EKASDPASSL RVAKTDSKTE EKTAASAPAN VSKGTTPLAP PPKPVRRRLK SEDELRPEVD 180
  181 EHTQKTGVLA AVLASQPSIP RSVGKDKKAI QASIRRNKET NTVLARLNSE LQQQLKDVLE 240
  241 ERISLEVQLE QLRPFSHL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle