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View Structure Prediction Details

Protein: SMARCC2
Organism: Homo sapiens
Length: 1214 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMARCC2.

Description E-value Query
Range
Subject
Range
gi|1549241 - gi|1549241|gb|AAC50694.1| SWI/SNF complex 170 KDa subunit [Homo sapiens]
0.0 [1..1203] [1..1202]
gi|55727092 - gi|55727092|emb|CAH90302.1| hypothetical protein [Pongo abelii]
gi|229576881 - gi|229576881|ref|NP_001153254.1| SWI/SNF related, matrix associated, actin dependent regulator of ch...
0.0 [1..1203] [1..1234]
SMRC2_MOUSE - SWI/SNF complex subunit SMARCC2 OS=Mus musculus GN=Smarcc2 PE=1 SV=2
0.0 [1..1203] [1..1202]
gi|61371200, gi|... - gi|61371200|gb|AAX43628.1| SWI/SNF related matrix associated actin dependent regulator of chromatin ...
0.0 [1..1083] [1..1113]
gi|109480100 - gi|109480100|ref|XP_001055795.1| PREDICTED: similar to SWI/SNF-related matrix-associated actin-depen...
0.0 [1..1203] [1..1205]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVRKKDGGP NVKYYEAADT VTQFDNVRLW LGKNYKKYIQ AEPPTNKSLS SLVVQLLQFQ  60
   61 EEVFGKHVSN APLTKLPIKC FLDFKAGGSL CHILAAAYKF KSDQGWRRYD FQNPSRMDRN 120
  121 VEMFMTIEKS LVQNNCLSRP NIFLCPEIEP KLLGKLKDII KRHQGTVTED KNNASHVVYP 180
  181 VPGNLEEEEW VRPVMKRDKQ VLLHWGYYPD SYDTWI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [217-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASEIEASVE DAPTPEKPRK VHAKWILDTD TFNEWMNEED YEVNDDKNPV SRRKKISAKT  60
   61 LTDEVNSPDS DRRDKKGGNY KKRKRSPSPS PTPEAKKKNA KKGPSTPYTK SKRGHREEEQ 120
  121 EDLTKDMDEP SPVPNVEEVT LPKTVNTKKD SESAPVKGGT MTDLDEQEDE SMETTGKDED 180
  181 ENSTGNKGEQ TKNPDLH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [414-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDNVTEQTHH IIIPSYAAWF DYNSVHAIER RALPEFFNGK NKSKTPEIYL AYRNFMIDTY  60
   61 RLNPQEYLTS TACRRNLAGD VCAIMRVHAF LEQWGLINYQ VDAESRPTPM GPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.39794
Match: 2fq3A
Description: Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [527-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSHFHVLAD TPSGLVPLQP KTPQQTSASQ QMLNFPDKGK EKPTDMQNFG LRTDMYTKKN  60
   61 VPSKSKAAAS ATREWTEQET LLLLEALEMY KDDWNKVSEH VGSRTQDECI LHFLRLPIED 120
  121 PYLEDSEASL GPLAYQPIPF SQSGNPVMST VAFLASVVDP RVASAAA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.83
Match: 2nogA
Description: No description for 2nogA was found.

Predicted Domain #5
Region A:
Residues: [694-1214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSALEEFSKM KEEVPTALVE AHVRKVEEAA KVTGKADPAF GLESSGIAGT TSDEPERIEE  60
   61 SGNDEARVEG QATDEKKEPK EPREGGGAIE EEAKEKTSEA PKKDEEKGKE GDSEKESEKS 120
  121 DGDPIVDPEK EKEPKEGQEE VLKEVVESEG ERKTKVERDI GEGNLSTAAA AALAAAAVKA 180
  181 KHLAAVEERK IKSLVALLVE TQMKKLEIKL RHFEELETIM DREREALEYQ RQQLLADRQA 240
  241 FHMEQLKYAE MRARQQHFQQ MHQQQQQPPP ALPPGSQPIP PTGAAGPPAV HGLAVAPASV 300
  301 VPAPAGSGAP PGSLGPSEQI GQAGSTAGPQ QQQPAGAPQP GAVPPGVPPP GPHGPSPFPN 360
  361 QQTPPSMMPG AVPGSGHPGV AGNAPLGLPF GMPPPPPPPA PSIIPFGSLA DSISINLPAP 420
  421 PNLHGHHHHL PFAPGTLPPP NLPVSMANPL HPNLPATTTM PSSLPLGPGL GSAAAQSPAI 480
  481 VAAVQGNLLP SASPLPDPGT PLPPDPTAPS PGTVTPVPPP Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.39794
Match: 1y0fB
Description: No description for 1y0fB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle