YRC Public Data Repository - Protein Structure Prediction

Protein:	LGALS4
Organism:	Homo sapiens
Length:	323 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LGALS4.

Description	E-value	Query Range	Subject Range
LEG4_MOUSE - Galectin-4 OS=Mus musculus GN=Lgals4 PE=1 SV=2 gi\|123253370, gi... - gi\|123253370\|gb\|ABM74073.1\| galectin-4 [Mus spretus], gi\|123253360\|gb\|ABM74072.1\| galectin-4 [Mus sp... gi\|123253350 - gi\|123253350\|gb\|ABM74071.1\| galectin-4 [Mus musculus domesticus] gi\|123253334 - gi\|123253334\|gb\|ABM74070.1\| galectin-4 [Mus musculus castaneus]	0.0	[1..323]	[1..326]
LEG4_RAT - Galectin-4 OS=Rattus norvegicus GN=Lgals4 PE=1 SV=1	0.0	[1..323]	[1..324]
gi\|61371621, gi\|... - gi\|61371627\|gb\|AAX43702.1\| lectin galactoside-binding soluble 4 [synthetic construct], gi\|61371621\|g...	0.0	[1..323]	[1..323]
gi\|130502092, gi... - gi\|5882169\|gb\|AAD55242.1\|AF091738_1 galectin-4 [Oryctolagus cuniculus], gi\|130502092\|ref\|NP_00107618...	0.0	[1..323]	[1..328]
LEG4_PIG - Galectin-4 OS=Sus scrofa GN=LGALS4 PE=2 SV=1 gi\|1082969 - pir\|\|A55664 lectin L-36 - pig	0.0	[1..323]	[1..323]
LEG4_BOVIN - Galectin-4 OS=Bos taurus GN=LGALS4 PE=2 SV=1	0.0	[1..323]	[1..332]
gi\|109124610 - gi\|109124610\|ref\|XP_001084043.1\| PREDICTED: galectin 4 [Macaca mulatta]	0.0	[1..323]	[1..324]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV  60
   61 AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP 120
  121 FYEYGHRLPL QMVTHLQVDG DLQLQSINFI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.221849
Match:	2dycA
Description:	No description for 2dycA was found.

Predicted Domain #2

Region A:
Residues: [151-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII  60
   61 KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP 120
  121 GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1x50A
Description:	Solution structure of the C-terminal gal-bind lectin domain from human galectin-4
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits