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View Structure Prediction Details

Protein: CRYBB1
Organism: Homo sapiens
Length: 252 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CRYBB1.

Description E-value Query
Range
Subject
Range
gi|9739217 - gi|9739217|gb|AAF97950.1|AF286652_1 betaB1-crystallin [Rattus norvegicus]
6.0E-91 [8..252] [1..245]
CRBB1_MOUSE - Beta-crystallin B1 OS=Mus musculus GN=Crybb1 PE=1 SV=3
2.0E-88 [1..252] [1..250]
gi|60654535 - gi|60654535|gb|AAX29958.1| crystallin beta B1 [synthetic construct]
3.0E-88 [15..252] [15..252]
gi|55660929 - gi|55660929|ref|XP_515047.1| PREDICTED: crystallin, beta B1 isoform 2 [Pan troglodytes]
1.0E-87 [15..252] [15..252]
gi|73995382 - gi|73995382|ref|XP_543459.2| PREDICTED: similar to crystallin, beta B1 [Canis familiaris]
3.0E-86 [1..252] [1..248]
CRBB1_PIG - Beta-crystallin B1 OS=Sus scrofa GN=CRYBB1 PE=2 SV=1
1.0E-81 [1..252] [1..249]

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Predicted Domain #1
Region A:
Residues: [1-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQAAKASAS ATVAVNPGPD TKGKGAPPAG TSPSPGTTLA PTTVPITSAK AAELPPGNYR  60
   61 LVVFELENFQ GRRAEFSGEC SNLADRGFDR VRSIIVSAGP WVAFEQSNFR GEMFILEKGE 120
  121 YPRWNTWSSS YRSDRLMSFR PIKMDAQEHK ISLFEGANFK GNTIEIQGDD APSLWVYGFS 180
  181 DRVGSVKVSS GTWVGYQYPG YRGYQYLLEP GDFRHWNEWG AFQPQMQSLR RLRDKQWHLE 240
  241 GSFPVLATEP PK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.045757
Match: 1okiA
Description: Crystal structure of truncated human beta-B1-crystallin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of eye lens 3.95613127220698 bayes_pls_golite062009
binding 1.49962891213419 bayes_pls_golite062009
protein binding 0.439215717175215 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle