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View Structure Prediction Details

Protein: TFDP1
Organism: Homo sapiens
Length: 410 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFDP1.

Description E-value Query
Range
Subject
Range
gi|24079969 - gi|24079969|gb|AAN46090.1| transcription factor Dp-1 [Homo sapiens]
0.0 [5..394] [1..390]
TFDP1_MOUSE - Transcription factor Dp-1 OS=Mus musculus GN=Tfdp1 PE=1 SV=1
0.0 [1..394] [1..394]
gi|73989562 - gi|73989562|ref|XP_849597.1| PREDICTED: similar to Transcription factor Dp-1 (E2F dimerization partn...
0.0 [5..394] [21..410]
TFDP1_BOVIN - Transcription factor Dp-1 OS=Bos taurus GN=TFDP1 PE=2 SV=1
0.0 [1..394] [1..394]
gi|50730508 - gi|50730508|ref|XP_416938.1| PREDICTED: similar to transcription factor [Gallus gallus]
0.0 [1..394] [1..395]
gi|114688131 - gi|114688131|ref|XP_521363.2| PREDICTED: similar to E2F-related transcription factor [Pan troglodyte...
0.0 [1..394] [1..393]
gi|52354615, gi|... - gi|52354615|gb|AAH82841.1| LOC494744 protein [Xenopus laevis], gi|148222844|ref|NP_001088050.1| hypo...
0.0 [1..393] [1..395]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKDAGLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVN PLGKQLLPKT FGQSNVNIAQ  60
   61 QVVIGTPQRP AASNTLVVGS PHTPSTHFAS QN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.205 0.622 transcription coactivator activity c.47.1 Thioredoxin-like

Predicted Domain #2
Region A:
Residues: [93-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPSDSSPWSA GKRNRKGEKN GKGLRHFSMK VCEKVQRKGT TSYNEVADEL VAEFSAADNH  60
   61 ILPNESAYDQ KNIRRRVYDA LNVLMAMNII SKEKKEIKWI GL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.522879
Match: 1cf7B
Description: Cell cycle transcription factor DP-2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [195-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTNSAQECQN LEVERQRRLE RIKQKQSQLQ ELILQQIAFK NLVQRNRHAE QQASRPPPPN  60
   61 SVIHLPFIIV NTSKKTVIDC SISNDKFEYL FNFDNTFEIH DDIEVLKRMG MACGLESGSC 120
  121 SAEDLKMARS LVPKALEPYV TEMAQGTVGG VFITTAGSTS NGTRFSASDL TNGADGMLAT 180
  181 SSNGSQYSGS RVETPVSYVG EDDEEDDDFN ENDEDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.69897
Match: 2azeA
Description: Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle