YRC Public Data Repository - Protein Structure Prediction

Protein:	CDC123
Organism:	Homo sapiens
Length:	336 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC123.

Description	E-value	Query Range	Subject Range
gi\|73949144 - gi\|73949144\|ref\|XP_535189.2\| PREDICTED: similar to D123 gene product [Canis familiaris]	0.0	[1..336]	[106..441]
CD123_MACFA - Cell division cycle protein 123 homolog OS=Macaca fascicularis GN=CDC123 PE=2 SV=1 gi\|109088205 - gi\|109088205\|ref\|XP_001083055.1\| PREDICTED: similar to D123 gene product [Macaca mulatta]	0.0	[1..336]	[1..336]
gi\|114629341, gi... - gi\|114629343\|ref\|XP_001136850.1\| PREDICTED: hypothetical protein isoform 9 [Pan troglodytes], gi\|114...	0.0	[1..336]	[1..336]
gi\|1435037, gi\|5... - gi\|5174423\|ref\|NP_006014.1\| D123 gene product [Homo sapiens], gi\|1435037\|dbj\|BAA03593.1\| protein D12...	0.0	[1..336]	[1..336]
CD123_RAT - Cell division cycle protein 123 homolog OS=Rattus norvegicus GN=Cdc123 PE=1 SV=1	0.0	[1..336]	[1..336]
CD123_MOUSE - Cell division cycle protein 123 homolog OS=Mus musculus GN=Cdc123 PE=1 SV=2	0.0	[1..336]	[1..336]
CD123_BOVIN - Cell division cycle protein 123 homolog OS=Bos taurus GN=CDC123 PE=2 SV=1	0.0	[1..336]	[1..335]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKEHVLHCQ FSAWYPFFRG VTIKSVILPL PQNVKDYLLD DGTLVVSGRD DPPTHSQPDS  60
   61 DDEAEEIQWS DDENTATLTA PEFPEFATKV QEAINSLGGS VFPKLNWSAP RDAYWIAMNS 120
  121 SLKCKTLSDI FLLFKSSDFI TRDFTQPF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [149-336]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHCTDDSPDP CIEYELVLRK WCELIPGAEF RCFVKENKLI GISQRDYTQY YDHISKQKEE  60
   61 IRRCIQDFFK KHIQYKFLDE DFVFDIYRDS RGKVWLIDFN PFGEVTDSLL FTWEELISEN 120
  121 NLNGDFSEVD AQEQDSPAFR CTNSEVTVQP SPYLSYRLPK DFVDLSTGED AHKLIDFLKL 180
  181 KRNQQEDD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits