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View Structure Prediction Details

Protein: RALY
Organism: Homo sapiens
Length: 306 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RALY.

Description E-value Query
Range
Subject
Range
gi|114681541 - gi|114681541|ref|XP_514591.2| PREDICTED: RNA binding protein (autoantigenic, hnRNP-associated with l...
1.0E-50 [1..306] [1..307]
gi|119596693, gi... - gi|74355073|gb|AAI03754.1| RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow h...
2.0E-50 [1..306] [1..307]
RALY_MOUSE - RNA-binding protein Raly OS=Mus musculus GN=Raly PE=1 SV=2
7.0E-50 [1..306] [1..312]
gi|109092331 - gi|109092331|ref|XP_001102633.1| PREDICTED: RNA binding protein, autoantigenic (hnRNP-associated wit...
7.0E-50 [1..306] [1..307]
gi|73992250 - gi|73992250|ref|XP_542969.2| PREDICTED: similar to RNA-binding protein Raly (hnRNP associated with l...
6.0E-49 [1..306] [1..293]
gi|76633747 - gi|76633747|ref|XP_881817.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
2.0E-47 [2..227] [81..304]
gi|58865494, gi|... - gi|58865494|ref|NP_001011958.1| RNA binding protein, autoantigenic (hnRNP-associated with lethal yel...
3.0E-47 [1..306] [1..295]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKLQASNV TNKNDPKSIN SRVFIGNLNT ALVKKSDVET IFSKYGRVAG CSVHKGYAFV  60
   61 QYSNERHARA AVLGENGRVL AGQTLDINMA GE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.30103
Match: 1wf1A
Description: Solution structure of RRM domain in RNA-binding protein NP_057951
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [93-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKPDRPKGLK RAASAIYSGY IFDYDYYRDD FYDRLFDYRG RLSPVPVPRA VPVKRPRVTV  60
   61 PLVRRVKTNV PVKLFARSTA VTTSSAKIKL KSSELQAIKT ELTQIKSNID ALLSRLEQIA 120
  121 AEQKANPDGK KKGDGGGAGG GGGGGGSGGG GSGGGGGGGS SRPPAPQENT TSEAGLPQGE 180
  181 ARTRDDGDEE GLLTHSEEEL EHSQDTDADD GALQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle