YRC Public Data Repository - Protein Structure Prediction

Protein:	TMEM115
Organism:	Homo sapiens
Length:	351 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TMEM115.

Description	E-value	Query Range	Subject Range
gi\|109039428, gi... - gi\|109039431\|ref\|XP_001099934.1\| PREDICTED: PL6 protein isoform 2 [Macaca mulatta], gi\|109039428\|ref...	5.0E-83	[1..351]	[1..351]
gi\|114587067 - gi\|114587067\|ref\|XP_516482.2\| PREDICTED: PL6 protein [Pan troglodytes]	1.0E-82	[1..351]	[1..351]
TM115_BOVIN - Transmembrane protein 115 OS=Bos taurus GN=TMEM115 PE=2 SV=1	2.0E-82	[1..351]	[1..351]
gi\|73985409 - gi\|73985409\|ref\|XP_850145.1\| PREDICTED: similar to PL6 protein (Placental protein 6) (PP6) isoform 3...	2.0E-81	[1..351]	[1..351]
gi\|34865897, gi\|... - gi\|34865897\|ref\|XP_343474.1\| PREDICTED: similar to Protein PL6 homolog [Rattus norvegicus], gi\|15781...	4.0E-81	[1..348]	[1..348]
TM115_MOUSE - Transmembrane protein 115 OS=Mus musculus GN=Tmem115 PE=1 SV=1 tr\|M0RAY5\|M0RAY5_RAT - Protein LOC100910557 OS=Rattus norvegicus GN=LOC100910557 PE=4 SV=1	2.0E-78	[1..348]	[1..348]
gi\|47197325 - gi\|47197325\|emb\|CAF89459.1\| unnamed protein product [Tetraodon nigroviridis]	7.0E-61	[1..311]	[3..315]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRALPGARQ HLGAILASAS VVVKALCAAV LFLYLLSFAV DTGCLAVTPG YLFPPNFWIW  60
   61 TLATHGLMEQ HVWDVAISLT TVVVAGRLLE PLWGALELLI FFSVVNVSVG LLGAFAYLLT 120
  121 YMASFNLVYL FTVRIHGALG FLGGVLVALK QTMGDCVVLR VPQVRVSVMP MLLLALLLLL 180
  181 RLATLLQSPA LASYGFGLLS SWVYLRFYQR HS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.522879
Match:	2nr9A
Description:	No description for 2nr9A was found.

Predicted Domain #2

Region A:
Residues: [213-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGRGDMADHF AFATFFPEIL QPVVGLLANL VHSLLVKVKI CQKTVKRYDV GAPSSITISL  60
   61 PGTDPQDAER RRQLALKALN ERLKRVEDQS IWPSMDDDEE ESGAKVDSPL PSDKAPTPPG 120
  121 KGAAPESSLI TFEAAPPTL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits