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View Structure Prediction Details

Protein: KCND1
Organism: Homo sapiens
Length: 647 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KCND1.

Description E-value Query
Range
Subject
Range
gi|8272404 - gi|8272404|dbj|BAA96454.1| shal-type potassium channel (Kv4.1) [Homo sapiens]
0.0 [1..647] [1..647]
gi|109130676 - gi|109130676|ref|XP_001104621.1| PREDICTED: similar to potassium voltage-gated channel, Shal-related...
0.0 [1..647] [1..647]
gi|74007389 - gi|74007389|ref|XP_855372.1| PREDICTED: similar to potassium voltage-gated channel, Shal-related sub...
0.0 [1..647] [1..647]
KCND1_MOUSE - Potassium voltage-gated channel subfamily D member 1 OS=Mus musculus GN=Kcnd1 PE=1 SV=1
0.0 [1..647] [1..651]
gi|149028439, gi... - gi|34933431|ref|XP_217601.2| PREDICTED: similar to Potassium voltage-gated channel subfamily D membe...
0.0 [1..647] [1..650]
KCND1_BOVIN - Potassium voltage-gated channel subfamily D member 1 OS=Bos taurus GN=KCND1 PE=2 SV=1
0.0 [1..647] [1..648]

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Predicted Domain #1
Region A:
Residues: [1-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAGLATWLP FARAAAVGWL PLAQQPLPPA PGVKASRGDE VLVVNVSGRR FETWKNTLDR  60
   61 YPDTLLGSSE KEFFYDADSG EYFFDRDPDM FRHVLNFYRT GRLHCPRQEC IQAFDEELAF 120
  121 YGLVPELVGD CCLEEYRDRK KENAERLAED EEAEQAGDGP ALPAGSSLRQ RLWRAFENPH 180
  181 TSTAALVFYY VTGFFIAVSV IANVVETIPC RGSARRSSRE QPCGERFPQA FFCMDTACVL 240
  241 IFTGEYLLRL FAAPSRCRFL RSVMSLIDVV AILPYYIGLL VPKNDDVSGA FVTLRVFRVF 300
  301 RIFKFSRHSQ GLRILGYTLK SCASELGFLL FSLTMAIIIF ATVMFYAEKG TNKTNFTSIP 360
  361 AAFWYTIVTM TTLGYGDMVP STIAGKIFGS ICSLSGVLVI ALPVPVIVSN FSRIYHQNQR 420
  421 ADKRRAQQKV RLARIRLAKS GTTNAFLQYK QNGGLEDSGS GEEQALCVRN RSAFEQQHHH 480
  481 LLHCLEKTTC HEFTDELTFS EALGAVSPGG R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.154902
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [512-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSRSTSVSSQ PVGPGSLLSS CCPRRAKRRA IRLANSTASV SRGSMQELDM LAGLRRSHAP  60
   61 QSRSSLNAKP HDSLDLNCDS RDFVAAIISI PTPPANTPDE SQPSSPGGGG RAGSTLRNSS 120
  121 LGTPCLFPET VKISSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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