YRC Public Data Repository - Protein Structure Prediction

Protein:	WBP4
Organism:	Homo sapiens
Length:	376 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WBP4.

Description	E-value	Query Range	Subject Range
gi\|114651365 - gi\|114651365\|ref\|XP_509769.2\| PREDICTED: similar to formin binding protein 21 [Pan troglodytes]	2.0E-58	[1..376]	[32..407]
gi\|109120555 - gi\|109120555\|ref\|XP_001089735.1\| PREDICTED: similar to WW domain-containing binding protein 4 isofor...	8.0E-53	[1..376]	[1..375]
WBP4_MOUSE - WW domain-binding protein 4 OS=Mus musculus GN=Wbp4 PE=1 SV=3	2.0E-52	[1..376]	[1..376]
WBP4_RAT - WW domain-binding protein 4 OS=Rattus norvegicus GN=Wbp4 PE=2 SV=1	2.0E-49	[1..376]	[1..374]
gi\|73989058 - gi\|73989058\|ref\|XP_534136.2\| PREDICTED: similar to WW domain-containing binding protein 4 isoform 1 ...	2.0E-48	[1..376]	[1..371]
gi\|115497466, gi... - gi\|115497466\|ref\|NP_001068719.1\| WW domain binding protein 4 [Bos taurus], gi\|109659172\|gb\|AAI18234....	1.0E-44	[1..376]	[1..395]

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Predicted Domain #1

Region A:
Residues: [1-113]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADYWKSQPK KFCDYCKCWI ADNRPSVEFH ERGKNHKENV AKRISEIKQK SLDKAKEEEK  60
   61 ASKEFAAMEA AALKAYQEDL KRLGLESEIL EPSITPVTST IPPTSTSNQQ KEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.0
Match:	1uw2A
Description:	The structure of the zinc finger from the human spliceosomal protein U1C
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [114-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEKKKRKKDP SKGRWVEGIT SEGYHYYYDL ISGASQWEKP EGFQGDLKKT AVKTVWVEGL  60
   61 SEDGFTYYYN TETGESRWEK PDDFIPHTSD LPSSKVNENS LGTLDESKSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.69897
Match:	1o6wA
Description:	Splicing factor prp40
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [224-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSHSDSDGEQ EAEEGGVSTE TEKPKIKFKE KNKNSDGGSD PETQKEKSIQ KQNSLGSNEE  60
   61 KSKTLKKSNP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [294-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGEWQEIKQE VESHEEVDLE LPSTENEYVS TSEADGGGEP KVVFKEKTVT SLGVMADGVA  60
   61 PVFKKRRTEN GKSRNLRQRG DDQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.045757
Match:	1uzcA
Description:	THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits