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View Structure Prediction Details

Protein: gi|194381058, gi...
Organism: Homo sapiens
Length: 804 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|194381058, gi....

Description E-value Query
Range
Subject
Range
gi|109013250 - gi|109013250|ref|XP_001092986.1| PREDICTED: adenosine monophosphate deaminase 2 (isoform L) isoform ...
0.0 [1..804] [1..804]
gi|73959323 - gi|73959323|ref|XP_537039.2| PREDICTED: similar to adenosine monophosphate deaminase 2 (isoform L) i...
0.0 [1..804] [1..804]
AMPD2 - adenosine monophosphate deaminase 2 (isoform L)
0.0 [3..804] [42..879]
AMPD2_RAT - AMP deaminase 2 OS=Rattus norvegicus GN=Ampd2 PE=1 SV=2
0.0 [25..803] [30..824]

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Predicted Domain #1
Region A:
Residues: [1-804]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWQSQAPAGA AQTPPLSPPW SQPWHPIHLA LASPRPNIPL RSGPACRPPL QLQELFTRSL  60
   61 AESELRSAPY EFPEESPIEQ LEERRQRLER QISQDVKLEP DILLRAKQDF LKTDSDSDLQ 120
  121 LYKEQGEGQG DRSLRERDVL EREFQRVTIS GEEKCGVPFT DLLDAAKSVV RALFIREKYM 180
  181 ALSLQSFCPT TRRYLQQLAE KPLETRTYEQ GPDTPVSADA PVHPPALEQH PYEHCEPSTM 240
  241 PGDLGLGLRM VRGVVHVYTR REPDEHCSEV ELPYPDLQEF VADVNVLMAL IINGPIKSFC 300
  301 YRRLQYLSSK FQMHVLLNEM KELAAQKKVP HRDFYNIRKV DTHIHASSCM NQKHLLRFIK 360
  361 RAMKRHLEEI VHVEQGREQT LREVFESMNL TAYDLSVDTL DVHADRNTFH RFDKFNAKYN 420
  421 PIGESVLREI FIKTDNRVSG KYFAHIIKEV MSDLEESKYQ NAELRLSIYG RSRDEWDKLA 480
  481 RWAVMHRVHS PNVRWLVQVP RLFDVYRTKG QLANFQEMLE NIFLPLFEAT VHPASHPELH 540
  541 LFLEHVDGFD SVDDESKPEN HVFNLESPLP EAWVEEDNPP YAYYLYYTFA NMAMLNHLRR 600
  601 QRGFHTFVLR PHCGEAGPIH HLVSAFMLAE NISHGLLLRK APVLQYLYYL AQIGIAMSPL 660
  661 SNNSLFLSYH RNPLPEYLSR GLMVSLSTDD PLQFHFTKEP LMEEYSIATQ VWKLSSCDMC 720
  721 ELARNSVLMS GFSHKVKSHW LGPNYTKEGP EGNDIRRTNV PDIRVGYRYE TLCQELALIT 780
  781 QAVQSEMLET IPEEAGITMS PGPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2a3lA
Description: X-Ray Structure of Adenosine 5'-Monophosphate Deaminase from Arabidopsis Thaliana in Complex with Coformycin 5'-Phosphate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.00269452684807 bayes_pls_golite062009
catalytic activity 1.70199291046899 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.12925526582667 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 0.248802326836448 bayes_pls_golite062009
dihydroorotase activity 0.203044795244555 bayes_pls_golite062009
deaminase activity 0.18698811376434 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.0954028693917728 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle