YRC Public Data Repository - Protein Structure Prediction

Protein:	SFN
Organism:	Homo sapiens
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SFN.

Description	E-value	Query Range	Subject Range
gi\|109087133 - gi\|109087133\|ref\|XP_001098275.1\| PREDICTED: similar to tyrosine 3/tryptophan 5 -monooxygenase activa...	0.0	[1..246]	[334..577]
gi\|68436321 - gi\|68436321\|ref\|XP_699659.1\| PREDICTED: similar to tyrosine 3-monooxygenase/tryptophan 5-monooxygena...	0.0	[1..246]	[1532..1775]
gi\|114576225 - gi\|114576225\|ref\|XP_525684.2\| PREDICTED: similar to 14.3.3 protein [Pan troglodytes]	0.0	[1..246]	[172..415]
gi\|17017334 - gi\|17017334\|gb\|AAL33624.1\|AF440230_1 protein kinase A activity reporter 1 fusion protein [synthetic ...	0.0	[1..236]	[232..465]
gi\|30354619 - gi\|30354619\|gb\|AAH51814.1\| YWHAZ protein [Homo sapiens]	0.0	[1..246]	[76..319]
gi\|73967154 - gi\|73967154\|ref\|XP_537764.2\| PREDICTED: similar to 14-3-3 protein epsilon (14-3-3E) (Mitochondrial i...	0.0	[2..238]	[3..239]
gi\|4775555 - gi\|4775555\|emb\|CAB42547.1\| 14-3-3-like protein [Pisum sativum]	0.0	[3..245]	[8..252]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR  60
   61 VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY 120
  121 LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH 180
  181 YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG 240
  241 EAPQEPQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1ywtA
Description:	Crystal structure of the human sigma isoform of 14-3-3 in complex with a mode-1 phosphopeptide
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits