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View Structure Prediction Details

Protein: gi|187951695, gi...
Organism: Homo sapiens
Length: 272 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|187951695, gi....

Description E-value Query
Range
Subject
Range
gi|21717632 - gi|21717632|gb|AAM76703.1|AF514992_1 nuclear protein p30 [Homo sapiens]
2.0E-73 [2..272] [1..271]
CENPV_MOUSE - Centromere protein V OS=Mus musculus GN=Cenpv PE=1 SV=2
5.0E-72 [1..272] [1..252]
gi|114688618 - gi|114688618|ref|XP_528984.2| PREDICTED: hypothetical protein [Pan troglodytes]
4.0E-68 [1..272] [16..276]
gi|109130803 - gi|109130803|ref|XP_001084846.1| PREDICTED: similar to proline rich 6 [Macaca mulatta]
1.0E-67 [1..272] [1..261]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRSRSSAAA KLRGQKRSGA SAAPAASAAA ALAPSATRTR RSASQAGSKS QAVEKPPSEK  60
   61 PRLRRSSPRA QEEGPGEPPP PELALLPPPP PPPPTPATPT SSASNLDLGE QRERWETFQK 120
  121 RQKLTSE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [128-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAAKLLLDTF EYQGLVKHTG GCHCGAVRFE VWASADLHIF DCNCSICKKK QNRHFIVPAS  60
   61 RFKLLKGAEH ITTYTFNTHK AQHTFCKRCG VQSFYTPRSN PGGFGIAPHC LDEGTVRSMV 120
  121 TEEFNGSDWE KAMKEHKTIK NMSKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1x6mA
Description: Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.566791077255496 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle