YRC Public Data Repository - Protein Structure Prediction

Protein:	GBAS
Organism:	Homo sapiens
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GBAS.

Description	E-value	Query Range	Subject Range
gi\|60653031, gi\|... - gi\|60653031\|gb\|AAX29210.1\| glioblastoma amplified sequence [synthetic construct], gi\|30585133\|gb\|AAP...	0.0	[1..286]	[1..286]
gi\|57087439 - gi\|57087439\|ref\|XP_536828.1\| PREDICTED: similar to NipSnap2 protein (Glioblastoma amplified sequence...	0.0	[1..286]	[1..286]
gi\|55742246 - ref\|NP_571109.1\| nipsnap2 [Danio rerio] NIPS2_DANRE - Protein NipSnap homolog 2 OS=Danio rerio GN=gbas PE=2 SV=2	0.0	[1..286]	[1..286]
gi\|2769254 - gi\|2769254\|emb\|CAA04633.1\| NIPSNAP2 protein [Homo sapiens]	0.0	[1..286]	[1..285]
gi\|114613443 - gi\|114613443\|ref\|XP_001158461.1\| PREDICTED: similar to GBAS isoform 4 [Pan troglodytes]	0.0	[13..286]	[13..286]
gi\|116004241, gi... - gi\|74356393\|gb\|AAI04623.1\| Glioblastoma amplified sequence [Bos taurus], gi\|116004241\|ref\|NP_0010704...	0.0	[1..286]	[1..286]
gi\|74213182, gi\|... - gi\|75832137\|ref\|NP_032121.2\| glioblastoma amplified [Mus musculus], gi\|74213182\|dbj\|BAE41726.1\| unna...	0.0	[1..286]	[1..281]
gi\|55778300, gi\|... - gi\|62945328\|ref\|NP_001017486.1\| glioblastoma amplified sequence [Rattus norvegicus], gi\|55778300\|gb\|...	0.0	[1..286]	[1..281]

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Predicted Domain #1

Region A:
Residues: [1-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARVLRARG AAWAGGLLQR AAPCSLLPRL RTWTSSSNRS REDSWLKSLF VRKVDPRKDA  60
   61 HSNLLAKKET SNLYKLQFHN VKPECLEAYN KICQEVLPKI HEDKHYPCTL VGTWNTWYGE 120
  121 QDQAVHLWRY EGGYPALTEV MNKLRENKEF LEFRKARSDM LLSRKNQLLL EFSFWNEPVP 180
  181 RSGP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.53
Match:	1vqyA
Description:	Crystal structure of hypothetical protein (np_396154.1) from Agrobacterium tumefaciens at 2.40 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [185-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIYELRSYQL RPGTMIEWGN YWARAIRFRQ DGNEAVGGFF SQIGQLYMVH HLWAYRDLQT  60
   61 REDIRNAAWH KHGWEELVYY TVPLIQEMES RIMIPLKTSP LQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.522879
Match:	1vqsA
Description:	Crystal structure of hypothetical protein (np_356412.1) from Agrobacterium tumefaciens at 1.50 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.0173015176171455	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: