YRC Public Data Repository - Protein Structure Prediction

Protein:	ARPC2
Organism:	Homo sapiens
Length:	300 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARPC2.

Description	E-value	Query Range	Subject Range
gi\|74195800 - gi\|74195800\|dbj\|BAE30463.1\| unnamed protein product [Mus musculus]	0.0	[1..300]	[84..383]
gi\|61372178, gi\|... - gi\|61372185\|gb\|AAX43797.1\| actin related protein 2/3 complex subunit 2 [synthetic construct], gi\|613...	0.0	[1..300]	[1..300]
ARPC2_BOVIN - Actin-related protein 2/3 complex subunit 2 OS=Bos taurus GN=ARPC2 PE=1 SV=1	0.0	[1..300]	[1..300]
gi\|34876797, gi\|... - ref\|XP_217432.2\| similar to actin related protein 2/3 complex subunit 2; ARP2/3 protein complex subu... tr\|G3IEK1\|G3IEK1... - Actin-related protein 2/3 complex subunit 2 OS=Cricetulus griseus GN=I79_022148 PE=4 SV=1	0.0	[1..300]	[1..300]
gi\|114583269 - gi\|114583269\|ref\|XP_516084.2\| PREDICTED: actin related protein 2/3 complex subunit 2 isoform 7 [Pan ...	0.0	[1..293]	[1..293]
gi\|109101026 - gi\|109101026\|ref\|XP_001088889.1\| PREDICTED: similar to actin related protein 2/3 complex subunit 2 [...	0.0	[1..293]	[1..293]
gi\|148233518, gi... - gi\|148233518\|ref\|NP_001090493.1\| hypothetical protein LOC779406 [Xenopus laevis], gi\|119352589\|gb\|AB...	0.0	[1..300]	[1..300]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILLEVNNRI IEETLALKFE NAAAGNKPEA VEVTFADFDG VLYHISNPNG DKTKVMVSIS  60
   61 LKFYKELQAH GADELLKRVY GSFLVNPESG YNVSLLYDLE NLPASKDSIV HQAGMLKRNC 120
  121 FASVFEKYFQ FQEEGKEGEN RAVIHYRDDE TMYVESKKDR VTVVFSTVFK DDDDVVIGKV 180
  181 FMQEFKEGRR ASHTAPQVLF SHREPPLELK DTDAAVGDNI GYITFVLFPR HTNASARDNT 240
  241 INLIHTFRDY LHYHIKCSKA YIHTRMRAKT SDFLKVLNRA RPDAEKKEMK TITGKTFSSR 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	154.0
Match:	1k8kD
Description:	ARPC2 (34 kDa subunit)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	6.0922573068519	bayes_pls_golite062009
actin filament binding	5.01990273175321	bayes_pls_golite062009
cytoskeletal protein binding	4.64781612293343	bayes_pls_golite062009
binding	2.16088008530271	bayes_pls_golite062009
protein binding	1.98253629760139	bayes_pls_golite062009
structural molecule activity	1.40122171600941	bayes_pls_golite062009
structural constituent of cytoskeleton	1.37010524302636	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: