YRC Public Data Repository - Protein Structure Prediction

Protein:	PHA2
Organism:	Saccharomyces cerevisiae
Length:	334 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHA2.

Description	E-value	Query Range	Subject Range
PHA2 - Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in... PHA2_YEAST - Putative prephenate dehydratase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHA2 PE=...	5.0E-92	[1..334]	[1..334]
PHEA_PSEST - P-protein OS=Pseudomonas stutzeri GN=pheA PE=3 SV=2	4.0E-84	[3..327]	[92..362]
gi\|254241854, gi... - gi\|84326074\|ref\|ZP_00974104.1\| COG0077: Prephenate dehydratase [Pseudomonas aeruginosa 2192], gi\|254... gi\|126168059, gi... - gi\|84319993\|ref\|ZP_00968379.1\| COG0077: Prephenate dehydratase [Pseudomonas aeruginosa C3719], gi\|25... PHEA_PSEAE - P-protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=pheA PE... gi\|107102696 - gi\|107102696\|ref\|ZP_01366614.1\| hypothetical protein PaerPA_01003762 [Pseudomonas aeruginosa PACS2] PHEA_PSEAE - P-protein OS=Pseudomonas aeruginosa GN=pheA PE=3 SV=1 gi\|116051155, gi... - gi\|46164072\|ref\|ZP_00204964.1\| COG0077: Prephenate dehydratase [Pseudomonas aeruginosa UCBPP-PA14], ...	3.0E-83	[3..327]	[92..362]
gi\|24983265, gi\|... - gi\|26988500\|ref\|NP_743925.1\| chorismate mutase [Pseudomonas putida KT2440], gi\|24983265\|gb\|AAN67389....	6.0E-83	[3..327]	[94..364]
gi\|213968719, gi... - gi\|213968719\|ref\|ZP_03396861.1\| chorismate mutase/prephenate dehydratase [Pseudomonas syringae pv. t... tr\|Q885T4\|Q885T4... - Chorismate mutase/prephenate dehydratase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=pheA ... gi\|28852193, gi\|... - gi\|28868953\|ref\|NP_791572.1\| chorismate mutase/prephenate dehydratase [Pseudomonas syringae pv. toma...	8.0E-83	[3..327]	[91..361]
gi\|162354353, gi... - gi\|77633065\|ref\|ZP_00795219.1\| COG0077: Prephenate dehydratase [Yersinia pestis Angola], gi\|16242153... gi\|152958934, gi... - gi\|77631815\|ref\|ZP_00794401.1\| COG0077: Prephenate dehydratase [Yersinia pseudotuberculosis IP 31758... Q66E50\|Q66E50_YERPS - Bifuctional: chorismate mutase and prephenate dehydratase - Yersinia pseudotuberculosis gi\|145600176, gi... - gi\|145600176\|ref\|YP_001164252.1\| bifunctional chorismate mutase/prephenate dehydratase [Yersinia pes... gi\|51595193, gi\|... - gi\|51595193\|ref\|YP_069384.1\| bifunctional chorismate mutase/prephenate dehydratase [Yersinia pseudot... gi\|45440256, gi\|... - gi\|45440256\|ref\|NP_991795.1\| bifunctional chorismate mutase/prephenate dehydratase [Yersinia pestis ... gi\|186697236, gi... - gi\|186894210\|ref\|YP_001871322.1\| bifunctional chorismate mutase/prephenate dehydratase [Yersinia pse... gi\|108774628, gi... - gi\|229901196\|ref\|ZP_04516319.1\| Chorismate mutase I / Prephenate dehydratase [Yersinia pestis Nepal5... gi\|229700459, gi... - gi\|229896385\|ref\|ZP_04511553.1\| Chorismate mutase I / Prephenate dehydratase [Yersinia pestis Pestoi...	8.0E-82	[7..329]	[104..378]
gi\|37525232, gi\|... - gi\|37525232\|ref\|NP_928576.1\| bifunctional chorismate mutase/prephenate dehydratase [Photorhabdus lum...	1.0E-81	[7..328]	[104..377]
PHEA_AQUAE - P-protein OS=Aquifex aeolicus (strain VF5) GN=pheA PE=3 SV=1 PHEA_AQUAE - P-protein OS=Aquifex aeolicus GN=pheA PE=4 SV=1	5.0E-81	[3..327]	[88..357]
gi\|11270737 - pir\|\|H81196 chorismate mutase/prephenate dehydratase NMB0446 [imported] - Neisseria meningitidis (st... gi\|7225671, gi\|1... - gi\|7225671\|gb\|AAF40883.1\| chorismate mutase/prephenate dehydratase [Neisseria meningitidis MC58], gi...	2.0E-80	[3..326]	[87..358]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKTLRVLF LGPKGTYSHQ AALQQFQSTS DVEYLPAASI PQCFNQLEND TSIDYSVVPL  60
   61 ENSTNGQVVF SYDLLRDRMI KKALSLPAPA DTNRITPDIE VIAEQYVPIT HCLISPIQLP 120
  121 NGIASLGNFE EVIIHSHPQV WGQVECYLRS MAEKFP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [157-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVTFIRLDCS STSESVNQCI RSSTADCDNI LHLAIASETA AQLHKAYIIE HSINDKLGNT  60
   61 TRFLVLKRR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [226-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENAGDNEVED TGLLRVNLLT FTTRQDDPGS LVDVLNILKI HSLNMCSINS RPFHLDEHDR  60
   61 NWRYLFFIEY YTEKNTPKNK EKFYEDISDK SKQWCLWGTF PRNERYYHK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.154902
Match:	1phzA_
Description:	Phenylalanine hydroxylase N-terminal domain; Phenylalanine hydroxylase, PAH
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits