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View Structure Prediction Details

Protein: IST2
Organism: Saccharomyces cerevisiae
Length: 946 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IST2.

Description E-value Query
Range
Subject
Range
IST2_YEAST - Increased sodium tolerance protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IST...
IST2 - Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small...
0.0 [1..915] [1..915]
gi|40354210 - gi|40354210|ref|NP_060513.4| transmembrane protein 16A [Homo sapiens]
0.0 [1..645] [201..940]
gi|110835696, gi... - gi|38614369|gb|AAH62959.1| Anoctamin 1, calcium activated chloride channel [Mus musculus], gi|148686...
0.0 [1..642] [201..933]
gi|85105158 - gi|85105158|ref|XP_961901.1| hypothetical protein [Neurospora crassa OR74A]
gi|32417002, gi|... - gi|32417002|ref|XP_328979.1| hypothetical protein [Neurospora crassa], gi|28923485|gb|EAA32665.1| hy...
0.0 [36..661] [133..726]

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Predicted Domain #1
Region A:
Residues: [1-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQTITSLDP NCVIVFNKTS SANEKSLNVE FKRLNIHSII EPGHDLQTSY AFIRIHQDNA  60
   61 KPLFSFLQNL DFIESIIPYH DTELSDDLHK LISISKSKIL EAPKQYELYN LSNLTNNPKQ 120
  121 SLYFAFLQNY IKWLIPFSFF GLSIRFLSNF TYEFNSTYSL FAILWTLSFT AFWLYKYEPF 180
  181 WSDRLSKYSS FSTIEFLQDK QKAQKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [207-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSVIMLKKC CFIPVALLFG AILLSFQLYC FALEIFIKQI YNGPMISILS FLPTILICTF  60
   61 TPVLTVIYNK YFVEPMTKWE NHSSVVNAKK SKEAKNFVII FLSSYVPLLI TLFLYLPMGH 120
  121 LLTAEIRTKV FNAFSILARL PTHDSDFIID TKRYEDQFFY FIVINQLIQF SMENFVPSLV 180
  181 SIAQQKINGP 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [397-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNFVKAESE IGKAQLSSSD MKIWSKVKSY QTDPWGATFD LDANFKKLLL QFGYLVMFST  60
   61 IWPLAPFICL IVNLIVYQVD LRKAVLYSKP EYFPFPIYDK PSSVSNTQKL TVGLWNSVLV 120
  121 MFSILGCVIT ATLTYMYQSC NIPGVGAHTS IHTNKAWYLA NPINHSWINI VLYAVFIEHV 180
  181 SVAIFFLFSS ILKSSHDDVA NGIVPKHVVN VQNPPKQEVF EKIPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [622-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEFNSNNEKE LVQRKGSANE KLHQELGEKQ PASSANGYEA HAATHANNDP SSLSSASSPS  60
   61 LSSSSSSSKT GVVKAVDNDT AGSAGKKPLA TESTEKRNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [721-946]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVKVPTVGSY GVAGATLPET IPTSKNYYLR FDEDGKSIRD AKSSAESSNA TNNNTLGTES  60
   61 KLLPDGDAVD ALSRKIDQIP KIAVTGGENN ENTQAKDDAA TKTPLIKDAN IKPVVNAAVN 120
  121 DNQSKVSVAT EQTKKTEVST KNGPSRSIST KETKDSARPS NNNTTTTTTT DATQPHHHHH 180
  181 HHRHRDAGVK NVTNNSKTTE SSSSSSAAKE KPKHKKGLLH KLKKKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle