YRC Public Data Repository - Protein Structure Prediction

Protein:	KRT20
Organism:	Homo sapiens
Length:	424 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRT20.

Description	E-value	Query Range	Subject Range
gi\|109481333 - gi\|109481333\|ref\|XP_001064779.1\| PREDICTED: similar to keratin Kb40 [Rattus norvegicus]	1.0E-66	[26..395]	[209..580]
gi\|73996557 - gi\|73996557\|ref\|XP_850166.1\| PREDICTED: similar to keratin, hair, basic, 3 [Canis familiaris]	2.0E-64	[3..383]	[128..515]
gi\|114625886 - gi\|114625886\|ref\|XP_520149.2\| PREDICTED: similar to OTTHUMP00000021786 [Pan troglodytes]	8.0E-62	[3..383]	[299..683]
gi\|109096771 - gi\|109096771\|ref\|XP_001093676.1\| PREDICTED: keratin, hair, basic, 4 [Macaca mulatta]	1.0E-61	[4..383]	[98..478]
gi\|46485130, gi\|... - gi\|47086911\|ref\|NP_997652.2\| keratin Kb40 [Mus musculus], gi\|46485130\|tpg\|DAA04930.1\| TPA: TPA_exp: ...	3.0E-61	[26..395]	[61..432]
KRT84 - keratin 84	4.0E-61	[7..383]	[101..478]

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Predicted Domain #1

Region A:
Residues: [1-424]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFSRRSFHR SLSSSLQAPV VSTVGMQRLG TTPSVYGGAG GRGIRISNSR HTVNYGSDLT  60
   61 GGGDLFVGNE KMAMQNLNDR LASYLEKVRT LEQSNSKLEV QIKQWYETNA PRAGRDYSAY 120
  121 YRQIEELRSQ IKDAQLQNAR CVLQIDNAKL AAEDFRLKYE TERGIRLTVE ADLQGLNKVF 180
  181 DDLTLHKTDL EIQIEELNKD LALLKKEHQE EVDGLHKHLG NTVNVEVDAA PGLNLGVIMN 240
  241 EMRQKYEVMA QKNLQEAKEQ FERQTAVLQQ QVTVNTEELK GTEVQLTELR RTSQSLEIEL 300
  301 QSHLSMKESL EHTLEETKAR YSSQLANLQS LLSSLEAQLM QIRSNMERQN NEYHILLDIK 360
  361 TRLEQEIATY RRLLEGEDVK TTEYQLSTLE ERDIKKTRKI KTVVQEVVDG KVVSSEVKEV 420
  421 EENI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.154902
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits