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View Structure Prediction Details

Protein: QCR2
Organism: Saccharomyces cerevisiae
Length: 368 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QCR2.

Description E-value Query
Range
Subject
Range
MPPB_MOUSE - Mitochondrial-processing peptidase subunit beta OS=Mus musculus GN=Pmpcb PE=1 SV=1
0.0 [1..368] [52..480]
gi|397699 - gi|397699|dbj|BAA03007.1| mitochondrial processing protease [Rattus norvegicus]
2.0E-99 [1..368] [50..478]
gi|3342006, gi|4... - gi|4758734|ref|NP_004270.1| peptidase (mitochondrial processing) beta [Homo sapiens], gi|3342006|gb|...
4.0E-99 [1..368] [52..480]
gi|195570810, gi... - gi|195570810|ref|XP_002103397.1| GD18983 [Drosophila simulans], gi|194199324|gb|EDX12900.1| GD18983 ...
gi|220945206, gi... - gi|220955020|gb|ACL90053.1| CG3731-PA [synthetic construct], gi|220945206|gb|ACL85146.1| CG3731-PA [...
gi|195328891, gi... - gi|195328891|ref|XP_002031145.1| GM24191 [Drosophila sechellia], gi|194120088|gb|EDW42131.1| GM24191...
CG3731-PB, CG3731-PA - This gene is referred to in FlyBase by the symbol Dmel\CG3731 (CG3731, FBgn0038271). It is a protein...
5.0E-98 [1..368] [35..461]
gi|12802327 - gi|12802327|gb|AAK07827.1|AF297643_1 mitochondrial processing peptidase beta subunit [Cucumis melo]
6.0E-89 [1..366] [88..517]
gi|587566 - gi|587566|emb|CAA56521.1| mitochondrial processing peptidase [Solanum tuberosum]
3.0E-88 [1..366] [93..523]
gi|3659967, gi|5... - gi|5822457|pdb|2BCC|A Chain A, Stigmatellin-Bound Cytochrome Bc1 Complex From Chicken, gi|3660376|pd...
8.0E-88 [3..368] [10..437]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
9.0E-88 [1..366] [93..523]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSAARLQFA QGSVRRLTVS ARDAPTKIST LAVKVHGGSR YATKDGVAHL LNRFNFQNTN  60
   61 TRSALKLVRE SELLGGTFKS TLDREYITLK ATFLKDDLPY YVNALADVLY KTAFKPHELT 120
  121 ESVLPAARYD YAV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [158-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLLYDGVERV SLQDIKDFAD KVYTKENLEV SGENVVEADL KRFVDESLLS TLPAGKSLVS  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10060.0
Match: 1ezvB_
Description: Cytochrome bc1 core subunit 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquinol-cytochrome-c reductase activity 10.0305725791312 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 10.0305725791312 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 6.64269017601856 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 4.17510847735476 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 4.03221088799464 bayes_pls_golite062009
oxidoreductase activity 3.89224384280888 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 3.48526983761385 bayes_pls_golite062009
cation transmembrane transporter activity 3.30443970063928 bayes_pls_golite062009
ion transmembrane transporter activity 3.14174223148448 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.79848305609896 bayes_pls_golite062009
substrate-specific transporter activity 2.6563825341516 bayes_pls_golite062009
binding 1.92389577633668 bayes_pls_golite062009
catalytic activity 1.30647052031202 bayes_pls_golite062009
protein binding 1.16040346226904 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [134-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEQCPVKSAE DQLYAITFRK GLGN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [218-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSEPKFFLGE ENRVRFIGDS VAAIGIPVNK ASLAQYEVLA NYLTSALSEL SGLISSAKLD  60
   61 KFTDGGLFTL FVRDQDSAVV SSNIKKIVAD LKKGKDLSPA INYTKLKNAV QNESVSSPIE 120
  121 LNFDAVKDFK LGKFNYVAVG DVSNLPYLDE L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10060.0
Match: 1ezvB_
Description: Cytochrome bc1 core subunit 2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle