YRC Public Data Repository - Protein Structure Prediction

Protein:	NUT2
Organism:	Saccharomyces cerevisiae
Length:	157 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUT2.

Description	E-value	Query Range	Subject Range
NUT2 - Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ... MED10_YEAST - Mediator of RNA polymerase II transcription subunit 10 OS=Saccharomyces cerevisiae (strain ATCC 2045... gi\|151942940 - gi\|151942940\|gb\|EDN61286.1\| mediator complex subunit [Saccharomyces cerevisiae YJM789] gi\|190408092 - gi\|190408092\|gb\|EDV11357.1\| RNA polymerase II holoenzyme 21 kDa mediator subunit [Saccharomyces cere...	7.0E-55	[1..157]	[1..157]
gi\|149032766, gi... - gi\|62663090\|ref\|XP_214417.3\| PREDICTED: similar to Mediator complex subunit 10 CG5057-PA [Rattus nor... MED10_MOUSE - Mediator of RNA polymerase II transcription subunit 10 OS=Mus musculus GN=Med10 PE=1 SV=1	2.0E-44	[11..149]	[1..133]
ENSCJAT00000016867 - null MED10_PONPY - Mediator of RNA polymerase II transcription subunit 10 - Pongo pygmaeus (Orangutan) MED10 - mediator complex subunit 10 gi\|114598920 - gi\|114598920\|ref\|XP_001143506.1\| PREDICTED: mediator of RNA polymerase II transcription, subunit 10 ... MED10_PONAB - Mediator of RNA polymerase II transcription subunit 10 OS=Pongo abelii GN=MED10 PE=2 SV=1 MED10_BOVIN - Mediator of RNA polymerase II transcription subunit 10 OS=Bos taurus GN=MED10 PE=2 SV=1	2.0E-44	[11..149]	[1..133]
MED10_NEUCR - Mediator of RNA polymerase II transcription subunit 10 OS=Neurospora crassa GN=nut-2 PE=3 SV=1 MED10_NEUCR - Mediator of RNA polymerase II transcription subunit 10 OS=Neurospora crassa (strain ATCC 24698 / 74-...	4.0E-39	[3..147]	[59..209]
mdt-10 - status:Confirmed UniProt:P45966 protein_id:CAA85334.1	6.0E-39	[8..145]	[37..168]
gi\|29841376 - gi\|29841376\|gb\|AAP06408.1\| SJCHGC01009 protein [Schistosoma japonicum]	3.0E-38	[15..144]	[7..128]
FBpp0305737, MED... - The gene Mediator complex subunit 10 is referred to in FlyBase by the symbol Dmel\MED10 (CG5057, FBg... gi\|195590683, gi... - gi\|195590683\|ref\|XP_002085074.1\| GD14606 [Drosophila simulans], gi\|194197083\|gb\|EDX10659.1\| GD14606 ... gi\|194119649, gi... - gi\|195328003\|ref\|XP_002030706.1\| GM25597 [Drosophila sechellia], gi\|194119649\|gb\|EDW41692.1\| GM25597...	7.0E-38	[11..145]	[1..130]
gi\|16323258, gi\|... - gi\|18396004\|ref\|NP_564254.1\| unknown protein [Arabidopsis thaliana], gi\|16323258\|gb\|AAL15363.1\| At1g...	1.0E-37	[7..148]	[35..165]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGNSTNNEQ LQQELATTQD QVASIIESFV ELGVSIYDFP GTPEATKGMI TNLQRNVDRL  60
   61 YKLNVRSNDP QSSLSKVDIP LEVVQYIEDG RNPDIYTREF VEAIRRSNQY QRGKMHGLKQ 120
  121 LRDSLADKIV DEFPELKEPV EDIIKRTSPI DNVSNTH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits