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View Structure Prediction Details

Protein: PIN3
Organism: Saccharomyces cerevisiae
Length: 215 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIN3.

Description E-value Query
Range
Subject
Range
PIN3 - Protein that induces appearance of [PIN+] prion when overproduced
PIN3_YEAST - [PSI+] inducibility protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PIN3 PE=1 ...
4.0E-42 [1..215] [1..215]
CSH3_SCHPO - Protein csh3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=csh3 PE=2 SV=1
SPBC119.05c - Wiskott-Aldrich syndrome homolog binding protein Lsb1
5.0E-30 [1..215] [83..296]
gi|17980553 - gi|17980553|gb|AAL50641.1|AF440203_1 Crk-based reporter [synthetic construct]
2.0E-29 [7..164] [323..478]
gi|3550240 - gi|3550240|gb|AAC36099.1| SH3 domain-containing adapter protein; CD2AP [Mus musculus]
7.0E-29 [6..194] [61..244]
gi|34365071 - gi|34365071|emb|CAE45892.1| hypothetical protein [Homo sapiens]
2.0E-28 [13..181] [318..491]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLINRSL TNIRTELDFL KGSNVISNDV YDQINKSLPA KWDPANAPRN ASPASLEYVE  60
   61 ALYQFDPQQD GDLGLKPGDK VQLLEKLSPE WYKGSCNGRT GIFPANYVKP AFSGSNGPSN 120
  121 LP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 161.503332
Match: 1griA_
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [123-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPQYKAQEL QQIPTQNSAA SSYQQQPFPP PSTNYYQQPQ QQPQQAPPPQ QQQQQQQHQS  60
   61 SHSHLKSFGS KLGNAAIFGA GASIGSDIVN NIF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.315 0.065 actin cytoskeleton organization a.1.1 Globin-like
View Download 0.453 0.020 nucleus a.59.1 PAH2 domain
View Download 0.408 0.018 actin cytoskeleton organization a.77.1 DEATH domain
View Download 0.569 0.013 nucleus a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.315 0.001 actin cytoskeleton organization a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.569 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.453 N/A N/A a.59.1 PAH2 domain
View Download 0.408 N/A N/A a.77.1 DEATH domain
View Download 0.315 N/A N/A a.1.1 Globin-like
View Download 0.315 N/A N/A a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.310 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.273 N/A N/A d.95.2 Homing endonucleases
View Download 0.270 N/A N/A c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.256 N/A N/A d.203.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
View Download 0.247 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.221 N/A N/A a.74.1 Cyclin-like
View Download 0.207 N/A N/A a.7.1 Spectrin repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle