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View Structure Prediction Details

Protein: OPY2
Organism: Saccharomyces cerevisiae
Length: 360 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OPY2.

Description E-value Query
Range
Subject
Range
OPY2 - Integral membrane protein that functions in the signaling branch of the high-osmolarity glycerol (HO...
OPY2_YEAST - Protein OPY2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OPY2 PE=1 SV=1
0.0 [1..360] [1..360]
gi|18376398 - gi|18376398|emb|CAD21287.1| related to OPY2 protein [Neurospora crassa]
8.0E-54 [7..214] [2..181]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-51 [66..280] [153..391]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSKASAS SSLSSTATSS TSATRGSDGC VVCDSTASCP VCASGEYCVM TSLTCDKCPS  60
   61 TYCAKQSDSQ LSSLSSSSSS SSSSNSNEKT SLIVGFTVGI VGGAMLIALV ALYFINKRYW 120
  121 KPKRQKNKAL KLEEASQSYG NEEEYFDDED DDDEDDEDDG GMRKDESHTL FNTSLVPPTL 180
  181 NVPGNRSSAS TTRTRASNIL PIAYIPGVTS GLSTDKLQSK LRSSSKRQNA AGDIRSHITL 240
  241 GSSILDG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [248-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDDEDDEHNQ VLNKDADDNL ITAIRAKPKL VQIAEEESDK EIQDLDVIEE QTEADDLSHM  60
   61 AKSEASHGNN DEDDDEEGSF ILDLEIPESI RESTQGSRTE SPFEDKFEIH DER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.387 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.335 a.26.1 4-helical cytokines
View Download 0.324 d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.469 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.313 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.299 d.93.1 SH2 domain
View Download 0.271 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.260 a.39.1 EF-hand
View Download 0.240 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.238 a.29.2 Bromodomain
View Download 0.224 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.222 a.3.1 Cytochrome c

Predicted Domain #3
Region A:
Residues: [198-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NILPIAYIPG VTSGLSTDKL QSKLRSSSKR QNAAGDIRSH ITLGSSILDG LDDEDDEHNQ  60
   61 VLNKDADDNL ITAIRAKPKL VQIAEEESDK EIQDLDVIEE QTEADDLSHM AKSEASHGNN 120
  121 DEDDDEEGSF ILDLEIPESI RESTQGSRTE SPFEDKFEIH DER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.469 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.387 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.384 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.335 a.26.1 4-helical cytokines
View Download 0.324 d.110.3 PYP-like sensor domain (PAS domain)


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle