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View Structure Prediction Details

Protein: RLF2
Organism: Saccharomyces cerevisiae
Length: 606 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RLF2.

Description E-value Query
Range
Subject
Range
RLF2 - Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles ...
gi|207340408 - gi|207340408|gb|EDZ68769.1| YPR018Wp-like protein [Saccharomyces cerevisiae AWRI1631]
RLF2_YEAST - Chromatin assembly factor 1 subunit p90 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
gi|151942807 - gi|151942807|gb|EDN61153.1| chromatin assembly factor-I (CAF-I) p90 subunit [Saccharomyces cerevisia...
gi|190407962 - gi|190407962|gb|EDV11227.1| chromatin assembly factor-I p90 subunit [Saccharomyces cerevisiae RM11-1...
2.0E-84 [1..606] [1..606]
gi|3668187 - gi|3668187|dbj|BAA33452.1| myosin heavy chain [Theragra chalcogramma]
2.0E-54 [5..362] [916..1274]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
2.0E-46 [5..416] [916..1328]
MYH1_HORSE - Myosin-1 OS=Equus caballus GN=MYH1 PE=2 SV=1
4.0E-46 [5..416] [917..1329]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
5.0E-46 [5..435] [919..1347]
gi|42476190, gi|... - gi|42476190|ref|NP_060004.2| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens], gi|...
8.0E-46 [5..435] [920..1348]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
1.0E-45 [5..471] [921..1384]

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Predicted Domain #1
Region A:
Residues: [1-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQHLKSIPL QDDTKKKGIL SFFQNTTTVK SNKFLTKEKD VITLDDPKED VSGPMIETVK  60
   61 QETMKSINKE CADEMKTTPK KANAEDKLLC YKNSPIQSTK YDRNTNKQVP NGNIIAIETK 120
  121 SRSSSPCSKR ELSSSKKEEA KREKELKKQQ RAEEKHRKEL LRQEEKKKKE LKVEEERQRR 180
  181 AELKKQKEEE KRRKEEARLE AKRRKEEERL KKEEEIRLKE EAKERAQSRI GNFFKKLSDS 240
  241 NTPVVEKSDY EKFFLPFYAK DGVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [265-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSNKWKLTKV ELEGSKRKID DELLNSKDKT SSDDLLNWLQ SRRLPRGHKI KRKAVDVLQQ  60
   61 MPLKEKTDDE LQSLLAQVPH KYIKFYENVR PPFIGTYSMD FTLPPNDPFS TKGTGFNYDY 120
  121 DSDVEWVNEE EEGEVDNLES GEEEEEEEDD EDVPSEGEFD GFLDSEENSD LDGLPCAKRK 180
  181 FVGPLIPTIC LKSNFENLSE ENKRYLQQLK AEVIIETDG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [484-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIDPFKEPKT SSLPSKRSNS DLQAQTASQS QSPEKKQKAM ITDPMDLLRL FDGVQDSTFS  60
   61 LGTVTEIAQK NLPQYNKQTI KNTIKEYAIR SSGKGDLPRK WVIKDAQNWE NLRANANMPT 120
  121 PSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.393 a.74.1 Cyclin-like
View Download 0.402 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.407 a.4.3 ARID-like
View Download 0.333 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.342 a.74.1 Cyclin-like
View Download 0.331 a.4.5 "Winged helix" DNA-binding domain
View Download 0.329 a.4.12 TrpR-like
View Download 0.306 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.294 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.292 d.79.5 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF
View Download 0.280 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.271 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.263 d.54.1 Enolase N-terminal domain-like
View Download 0.255 d.79.1 YjgF-like
View Download 0.253 a.118.11 Cytochrome c oxidase subunit E
View Download 0.252 a.4.1 Homeodomain-like
View Download 0.247 a.74.1 Cyclin-like
View Download 0.246 a.64.1 Saposin
View Download 0.233 a.1.1 Globin-like
View Download 0.224 c.50.1 Macro domain-like
View Download 0.216 a.1.1 Globin-like
View Download 0.213 a.39.1 EF-hand
View Download 0.209 a.118.8 TPR-like
View Download 0.209 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.207 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.204 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.202 a.4.1 Homeodomain-like

Predicted Domain #4
Region A:
Residues: [418-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSEGEFDGFL DSEENSDLDG LPCAKRKFVG PLIPTICLKS NFENLSEENK RYLQQLKAEV  60
   61 IIETDGPIDP FKEPKTSSLP SKRSNSDLQA QTASQSQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [515-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPEKKQKAMI TDPMDLLRLF DGVQDSTFSL GTVTEIAQKN LPQYNKQTIK NTIKEYAIRS  60
   61 SGKGDLPRKW VIKDAQNWEN LRANANMPTP SL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.393 a.74.1 Cyclin-like
View Download 0.402 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.407 a.4.3 ARID-like
View Download 0.381 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.342 a.74.1 Cyclin-like


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