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View Structure Prediction Details

Protein: YPR003C
Organism: Saccharomyces cerevisiae
Length: 754 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPR003C.

Description E-value Query
Range
Subject
Range
gi|13625941, gi|... - gi|162464404|ref|NP_001105050.1| sulfate transporter ST1 [Zea mays], gi|13625941|gb|AAK35215.1|AF355...
0.0 [32..714] [5..653]
gi|24421075 - gi|24421075|emb|CAD55695.1| sulphate transporter [Aegilops speltoides]
0.0 [32..714] [4..657]
SULX_YEAST - Putative sulfate transporter YPR003C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPR...
YPR003C - Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion ...
gi|190407947 - gi|190407947|gb|EDV11212.1| hypothetical protein SCRG_02492 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..754] [1..754]
gi|4850271 - gi|4850271|emb|CAB42985.1| putative high affinity sulfate transporter [Aegilops tauschii]
0.0 [32..714] [4..657]
gi|24421089 - gi|24421089|emb|CAD55702.1| sulphate transporter [Triticum aestivum]
0.0 [32..714] [4..657]
gi|28300414, gi|... - gi|28300414|gb|AAO34714.1| high-affinity sulfate transporter HvST1 [Hordeum vulgare subsp. vulgare],...
0.0 [32..714] [4..655]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [32..714] [4..655]
gi|14484936 - gi|14484936|gb|AAK62820.1| high affinity sulfate transporter [Lycopersicon esculentum]
0.0 [35..716] [4..650]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSNNSLLGR GRMSYSSTAP PRFKRSVDQR DTFSDNFDYD KDSSNRGRTY IAASNSTTGV  60
   61 PPPNNSRSGC TNNTNNTNNT SNTSNTNNND 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.442 c.13.2 Anti-sigma factor antagonist SpoIIaa

Predicted Domain #2
Region A:
Residues: [91-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVDENTVFET LPYYLPCFSW LPEYTFNKLW GDVIAGISVA SFQIPLALSY TTSIAHVPPL  60
   61 CGLYSLAISP FVYGILGSVP QMIVGPESAI SLVVGQAVES ITLHK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.994 N/A N/A a.24.4 Hemerythrin
View Download 0.994 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.987 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.981 N/A N/A a.24.3 Cytochromes
View Download 0.978 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #3
Region A:
Residues: [196-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENVSLIDIST VITFVSGTIL LFSGISRFGF LGNVLSKALL RGFISSVGLV MIINSLISEL  60
   61 KLDKFLVSLP QHYHTPFEKI LFLIDYAPAQ YHIPTAIFSG CCLIVLFLTR LLKRKLMKYH 120
  121 KSAIFFPDIL LVVIVTILIS MKFNLKHRYG ISIIGDFSMD NFDELKNPLT RPRRKLIPDL 180
  181 FSASLIVAML GFFESTTASK SLGTTYNLTV SSNRELVALG FMNIVISLFG ALPAFGGYGR 240
  241 SKINALSGAQ SVMSGVFMGV ITLITMNLLL QFVHYIPNCV LSVITTIIGI SLLEEVPGDI 300
  301 KFHLRCGGFS ELFVFAVTFC TTIFYSIEAG ICIGCVYSII NIIKHSAKSR IQILARVAG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 112.05061
Match: PF00916
Description: Sulfate transporter family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [555-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSNFTNLDDY MMNMKRNSLD VEGTEEIEGC MIVRIPEPLT FTNSEDLKQR LDRIERYGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.460 a.4.5 "Winged helix" DNA-binding domain
View Download 0.368 a.20.1 PGBD-like
View Download 0.424 a.140.2 SAP domain
View Download 0.558 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.500 a.64.2 Bacteriocin AS-48
View Download 0.365 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.361 a.20.1 PGBD-like
View Download 0.352 a.144.1 PABC (PABP) domain
View Download 0.340 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.310 a.64.1 Saposin
View Download 0.293 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.271 a.156.1 S13-like H2TH domain
View Download 0.258 a.4.1 Homeodomain-like
View Download 0.253 a.28.1 ACP-like
View Download 0.247 a.4.1 Homeodomain-like
View Download 0.223 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.209 a.20.1 PGBD-like
View Download 0.205 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.204 d.59.1 Ribosomal protein L30p/L7e
View Download 0.204 a.140.1 LEM domain
View Download 0.201 a.28.3 Retrovirus capsid protein C-terminal domain

Predicted Domain #5
Region A:
Residues: [614-754]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKIHPGRKSL RSKDSIKYVI FDLGGMTSID SSAAQVLEEI ITSYKRRNVF IYLVNVSIND  60
   61 KVRRRLFKAG VAASVERAQA NNNENNTSNT FSDAGETYSP YFDSIDAALY EIEKMKIKGN 120
  121 NVPNNDSESF MSNTLFNSSL V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.0
Match: 1auz__
Description: Anti-sigma factor antagonist SpoIIaa
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [578-754]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEEIEGCMIV RIPEPLTFTN SEDLKQRLDR IERYGSSKIH PGRKSLRSKD SIKYVIFDLG  60
   61 GMTSIDSSAA QVLEEIITSY KRRNVFIYLV NVSINDKVRR RLFKAGVAAS VERAQANNNE 120
  121 NNTSNTFSDA GETYSPYFDS IDAALYEIEK MKIKGNNVPN NDSESFMSNT LFNSSLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1auzA
Description: SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS, NMR, 24 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.9933616198208 bayes_pls_golite062009
protein binding 1.73254574073085 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle