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View Structure Prediction Details

Protein: SUI3
Organism: Saccharomyces cerevisiae
Length: 285 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SUI3.

Description E-value Query
Range
Subject
Range
SUI3 - Beta subunit of the translation initiation factor eIF2, involved in the identification of the start ...
IF2B_YEAST - Eukaryotic translation initiation factor 2 subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204...
4.0E-86 [1..285] [1..285]
IF2B_WHEAT - Eukaryotic translation initiation factor 2 subunit beta OS=Triticum aestivum PE=1 SV=1
2.0E-70 [29..284] [2..268]
gi|50940043, gi|... - gi|50940043|ref|XP_479549.1| putative translation initiation factor eIF-2 beta chain [Oryza sativa (...
1.0E-68 [28..284] [3..268]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-68 [1..285] [1..328]
IF2B_MOUSE - Eukaryotic translation initiation factor 2 subunit 2 OS=Mus musculus GN=Eif2s2 PE=1 SV=1
5.0E-68 [1..285] [1..326]
IF2B_RABIT - Eukaryotic translation initiation factor 2 subunit 2 OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
6.0E-68 [1..285] [1..328]
gi|123995017, gi... - gi|123995017|gb|ABM85110.1| eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa [synth...
gi|12654229 - gi|12654229|gb|AAH00934.1| Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa [Homo s...
9.0E-68 [1..285] [1..328]
gi|45382971, gi|... - gi|45382971|ref|NP_989928.1| eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa [Gall...
3.0E-67 [1..285] [1..329]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDLAAELG FDPALKKKKK TKKVIPDDFD AAVNGKENGS GDDLFAGLKK KKKKSKSVSA  60
   61 DAEAEKEPTD DIAEALGELS LKKKKKKTKD SSVDAFEKEL AKAGLDNVDA ESKEGTPSAN 120
  121 SSIQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.531 0.225 ribosome a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.454 0.042 translation initiation factor activity a.133.1 Phospholipase A2, PLA2
View Download 0.565 0.018 translation initiation factor activity a.118.8 TPR-like
View Download 0.515 0.006 translation initiation factor activity a.29.2 Bromodomain
View Download 0.469 0.001 translation initiation factor activity f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.565 N/A N/A a.118.8 TPR-like
View Download 0.531 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.515 N/A N/A a.29.2 Bromodomain
View Download 0.488 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.469 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.430 N/A N/A a.118.1 ARM repeat
View Download 0.426 N/A N/A a.90.1 Transcription factor STAT-4 N-domain
View Download 0.413 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.403 N/A N/A a.5.4 Elongation factor TFIIS domain 2
View Download 0.385 N/A N/A a.47.2 t-snare proteins
View Download 0.382 N/A N/A d.58.34 Formiminotransferase domain of formiminotransferase-cyclodeaminase.
View Download 0.365 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.343 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.338 N/A N/A a.19.1 Fertilization protein
View Download 0.330 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.326 N/A N/A a.130.1 Chorismate mutase II
View Download 0.325 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.320 N/A N/A a.24.3 Cytochromes
View Download 0.316 N/A N/A a.118.8 TPR-like
View Download 0.306 N/A N/A a.1.1 Globin-like
View Download 0.291 N/A N/A a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.285 N/A N/A a.26.1 4-helical cytokines
View Download 0.280 N/A N/A d.15.5 Staphylokinase/streptokinase
View Download 0.275 N/A N/A a.26.1 4-helical cytokines
View Download 0.274 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.268 N/A N/A a.1.1 Globin-like
View Download 0.258 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.254 N/A N/A i.1.1 Ribosome and ribosomal fragments
View Download 0.252 N/A N/A a.74.1 Cyclin-like
View Download 0.248 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.233 N/A N/A a.182.1 GatB/YqeY domain
View Download 0.215 N/A N/A a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.205 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.205 N/A N/A a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.204 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.200 N/A N/A a.7.6 Ribosomal protein S20

Predicted Domain #2
Region A:
Residues: [125-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEVGLPYSEL LSRFFNILRT NNPELAGDRS GPKFRIPPPV CLRDGKKTIF SNIQDIAEKL  60
   61 HRSPEHLIQY LFAELGTSGS VDGQKRLVIK GKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1k8bA_
Description: Zinc-binding domain of translation initiation factor 2 beta
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [218-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSKQMENVLR RYILEYVTCK TCKSINTELK REQSNRLFFM VCKSCGSTRS VSSIKTGFQA  60
   61 TVGKRRRM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1k81A_
Description: Zinc-binding domain of translation initiation factor 2 beta
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle