YRC Public Data Repository - Protein Structure Prediction

Protein:	POS5
Organism:	Saccharomyces cerevisiae
Length:	414 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POS5.

Description	E-value	Query Range	Subject Range
POS5 - Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; r... POS5_YEAST - NADH kinase POS5, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POS5 PE=...	0.0	[1..414]	[1..414]
gi\|26988737, gi\|... - gi\|26988737\|ref\|NP_744162.1\| inorganic polyphosphate/ATP-NAD kinase [Pseudomonas putida KT2440], gi\|...	2.0E-86	[54..388]	[11..315]
gi\|12804579, gi\|... - gi\|20070086\|gb\|AAM01195.1\| NAD kinase [Homo sapiens], gi\|12804579\|gb\|AAH01709.1\| FLJ13052 protein [H...	1.0E-85	[27..410]	[65..433]
PPNK_MOUSE, NADK... - (P58058) Putative inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase), NAD...	1.0E-84	[27..410]	[65..429]
CG33156-PA - This gene is referred to in FlyBase by the symbol Dmel\CG33156 (CG33156, FBgn0053156). It is a prote... gi\|220950314 - gi\|220950314\|gb\|ACL87700.1\| CG33156-PA [synthetic construct]	9.0E-84	[27..410]	[64..425]
PPNK_PSEAE - Probable inorganic polyphosphate/ATP-NAD kinase OS=Pseudomonas aeruginosa GN=ppnK PE=3 SV=1 gi\|254236059, gi... - gi\|84320254\|ref\|ZP_00968638.1\| COG0061: Predicted sugar kinase [Pseudomonas aeruginosa C3719], gi\|25... NADK_PSEA8 - NAD kinase OS=Pseudomonas aeruginosa (strain LESB58) GN=nadK PE=3 SV=1 NADK_PSEAB - NAD kinase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=nadK PE=3 SV=1 NADK_PSEA7 - NAD kinase OS=Pseudomonas aeruginosa (strain PA7) GN=nadK PE=3 SV=1 NADK_PSEAE - NAD kinase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=nadK P... gi\|107102637 - gi\|107102637\|ref\|ZP_01366555.1\| hypothetical protein PaerPA_01003701 [Pseudomonas aeruginosa PACS2]	3.0E-83	[66..379]	[3..287]

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Predicted Domain #1

Region A:
Residues: [1-97]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVRVKLNKP VKWYRFYSTL DSHSLKLQSG SKFVKIKPVN NLRSSSSADF VSPPNSKLQS  60
   61 LIWQNPLQNV YITKKPWTPS TREAMVEFIT HLHESYP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [98-414]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVNVIVQPDV AEEISQDFKS PLENDPNRPH ILYTGPEQDI VNRTDLLVTL GGDGTILHGV  60
   61 SMFGNTQVPP VLAFALGTLG FLSPFDFKEH KKVFQEVISS RAKCLHRTRL ECHLKKKDSN 120
  121 SSIVTHAMND IFLHRGNSPH LTNLDIFIDG EFLTRTTADG VALATPTGST AYSLSAGGSI 180
  181 VSPLVPAILM TPICPRSLSF RPLILPHSSH IRIKIGSKLN QKPVNSVVKL SVDGIPQQDL 240
  241 DVGDEIYVIN EVGTIYIDGT QLPTTRKTEN DFNNSKKPKR SGIYCVAKTE NDWIRGINEL 300
  301 LGFNSSFRLT KRQTDND

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	109.337242
Match:	PF01513
Description:	ATP-NAD kinase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits