YRC Public Data Repository - Protein Structure Prediction

Protein:	SPT14
Organism:	Saccharomyces cerevisiae
Length:	452 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPT14.

Description	E-value	Query Range	Subject Range
GPI3_YEAS6 - Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit OS=Saccharomyces cerevisiae (strai... GPI3_YEAST - Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit OS=Saccharomyces cerevisiae (strai... SPT14 - UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosp... GPI3_YEAS1 - Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit OS=Saccharomyces cerevisiae (strai...	4.0E-84	[1..452]	[1..452]
gi\|46108156, gi\|... - gi\|46108156\|ref\|XP_381136.1\| hypothetical protein FG00960.1 [Gibberella zeae PH-1], gi\|42546668\|gb\|E...	2.0E-78	[4..451]	[7..484]
PIGA_MOUSE - N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein OS=Mus musculus GN=Piga PE=2 SV=1 gi\|7441626, gi\|3... - pir\|\|I52484 gene PIG-A protein - mouse, gi\|30387809\|gb\|AAP32009.1\| PIG-A [Mus sp.]	2.0E-77	[4..452]	[34..484]
gi\|34880068, gi\|... - gi\|34880068\|ref\|XP_343784.1\| PREDICTED: similar to N-acetylglucosaminyl-phosphatidylinositol biosynt...	4.0E-76	[4..452]	[34..484]
gi\|45184716, gi\|... - gi\|45184716\|ref\|NP_982434.1\| AAL108Cp [Ashbya gossypii ATCC 10895], gi\|44980062\|gb\|AAS50258.1\| AAL10... gi\|44980062 - gi\|44980062\|gb\|AAS50258.1\| AAL108Cp [Ashbya gossypii ATCC 10895]	3.0E-75	[3..440]	[5..436]
gi\|49085278, gi\|... - gi\|67516709\|ref\|XP_658240.1\| hypothetical protein AN0636.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	1.0E-74	[1..450]	[1..481]
gi\|45593796 - gi\|45593796\|gb\|AAS68360.1\| phosphatidylinositol:UDP-GlcNAc transferase PIG-A [Aspergillus fumigatus]	1.0E-73	[7..448]	[1..473]
PIGA - phosphatidylinositol glycan anchor biosynthesis, class A	4.0E-73	[4..436]	[34..456]

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Predicted Domain #1

Region A:
Residues: [1-383]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFNIAMLCD FFYPQLGGVE FHIYHLSQKL IDLGHSVVII THAYKDRVGV RHLTNGLKVY  60
   61 HVPFFVIFRE TTFPTVFSTF PIIRNILLRE QIQIVHSHGS ASTFAHEGIL HANTMGLRTV 120
  121 FTDHSLYGFN NLTSIWVNKL LTFTLTNIDR VICVSNTCKE NMIVRTELSP DIISVIPNAV 180
  181 VSEDFKPRDP TGGTKRKQSR DKIVIVVIGR LFPNKGSDLL TRIIPKVCSS HEDVEFIVAG 240
  241 DGPKFIDFQQ MIESHRLQKR VQLLGSVPHE KVRDVLCQGD IYLHASLTEA FGTILVEAAS 300
  301 CNLLIVTTQV GGIPEVLPNE MTVYAEQTSV SDLVQATNKA INIIRSKALD TSSFHDSVSK 360
  361 MYDWMDVAKR TVEIYTNISS TSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.69897
Match:	1o6cB_
Description:	Crystal structure of UDP-N-acetylglucosamine 2-epimerase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [384-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADDKDWMKMV ANLYKRDGIW AKHLYLLCGI VEYMLFFLLE WLYPRDEIDL APKWPKKTVS  60
   61 NETKEARET

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits