YRC Public Data Repository - Protein Structure Prediction

Protein:	NOP53
Organism:	Saccharomyces cerevisiae
Length:	455 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOP53.

Description	E-value	Query Range	Subject Range
NOP53_YEAST - Ribosome biogenesis protein NOP53 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP53 ... NOP53 - Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA pr...	4.0E-43	[1..455]	[1..455]
gi\|8163674 - gi\|8163674\|gb\|AAF73795.1\|AF154026_1 surface protein PspC [Streptococcus pneumoniae]	5.0E-43	[61..419]	[51..408]
gi\|11353751 - pir\|\|A81937 IgA-specific metalloendopeptidase (EC 3.4.24.13) NMA0905 [imported] - Neisseria meningit... gi\|121051831, gi... - gi\|7379617\|emb\|CAB84182.1\| IgA1 protease [Neisseria meningitidis Z2491], gi\|218767823\|ref\|YP_0023423...	1.0E-39	[161..453]	[943..1231]
gi\|7225928, gi\|1... - gi\|7225928\|gb\|AAF41117.1\| IgA-specific serine endopeptidase [Neisseria meningitidis MC58], gi\|156765... gi\|11353752 - pir\|\|C81169 IgA-specific metalloendopeptidase (EC 3.4.24.13) NMB0700 [imported] - Neisseria meningit...	4.0E-39	[161..453]	[943..1235]
gi\|21539653, gi\|... - gi\|21539653\|ref\|NP_598592.1\| glioma tumor suppressor candidate region gene 2 [Mus musculus], gi\|1716...	2.0E-38	[1..455]	[25..483]
gi\|8574093 - gi\|8574093\|emb\|CAB94786.1\| GLTSCR2, glioma tumor suppressor candidate region protein 2 (AF182076_1) ...	3.0E-38	[1..455]	[6..458]
gi\|7549210 - gi\|7549210\|gb\|AAF63787.1\|AF142406_1 200 kDa antigen p200 [Babesia bigemina]	3.0E-38	[4..453]	[202..652]

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Predicted Domain #1

Region A:
Residues: [1-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPTNLTKKP SQYKQSSRKG KKAWRKNIDL SDVEQYMEKK IDHEITHGTS DITSLQNDAL  60
   61 FHVDVEGDEI LKNKLIKRKQ IKKVLKSKEI LDAVKTNSKI AALNHHKNSS GNPNKIQGVS 120
  121 KHELKKLMAL AGRVHGESKI KNRVAKDGLV KTTAGDLWGE ESNSKKQKVK LPSGIKLDVE 180
  181 KKDQIPEELL KKSTTSWSTA SVRPSTLDIE PIAVKEFTEI PHAGKSYNPN NKAWSELINK 240
  241 EYKEEKARED ERIALEKYKE RIRHLMETLD DNEEEESSSN EEEEEEEEEN ENENESTQCS 300
  301 GSDKEIKLSI NKPVKNKKKT KYQRNKAKRH EEKVKLQQEL KELRQRVKDL EEVINSEETE 360
  361 ILSAIESDSN KVKKSKKNKK HKLGT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.30103
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [386-455]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYSVIDERLE IKFSDELSDS LRKLKPEGNL LYDTVRKLQS SGKVETRVPV RKGRKYKQKI  60
   61 TEKWTHKDFK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits