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View Structure Prediction Details

Protein: KES1
Organism: Saccharomyces cerevisiae
Length: 434 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KES1.

Description E-value Query
Range
Subject
Range
KES1_YEAST - Oxysterol-binding protein homolog 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KES1...
gi|151942655 - gi|151942655|gb|EDN61001.1| kre11-1 suppressor [Saccharomyces cerevisiae YJM789]
KES1 - Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in neg...
0.0 [1..434] [1..434]
gi|14042387 - gi|14042387|dbj|BAB55223.1| unnamed protein product [Homo sapiens]
0.0 [5..399] [352..716]
gi|9651091 - gi|9651091|dbj|BAB03558.1| hypothetical protein [Macaca fascicularis]
0.0 [5..399] [373..737]
OSBL1_RAT - Oxysterol-binding protein-related protein 1 OS=Rattus norvegicus GN=Osbpl1a PE=1 SV=1
0.0 [1..385] [541..939]

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Predicted Domain #1
Region A:
Residues: [1-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQYASSSSW TSFLKSIASF NGDLSSLSAP PFILSPISLT EFSQYWAEHP ELFLEPSFIN  60
   61 DDNYKEHCLI DPEVESPELA RMLAVTKWFI STLKSQYCSR NESLGSEKKP LNPFLGELFV 120
  121 GKWENKEHPE FGETVLLSEQ VSHHPPVTAF SIFNDKNKVK LQGYNQIKAS FTKSLMLTVK 180
  181 QFGHTMLDIK DESYLVTPPP LHIEGILVAS PFVELEGKSY IQSSTGLLCV IEFSGRGYFS 240
  241 GKKNSFKARI YKDSKDSKDK EKALYTISGQ WSGSSKIIKA NKKEESRLFY DAARIPAEHL 300
  301 NVKPLEEQHP LESRKAWYDV AGAIKLGDFN LIAKTKTELE ETQRELRKEE EAKGISWQRR 360
  361 WFKDFDYSVT PEEGALVPEK DDTFLKLASA LNLSTKNAPS GTLVGDKEDR KEDLSSIHWR 420
  421 FQRELWDEEK EIVL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 233.130768
Match: PF01237
Description: Oxysterol-binding protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
oxysterol binding 5.62675037461468 bayes_pls_golite062009
sterol binding 4.18891468109664 bayes_pls_golite062009
3.02967613614595 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
phosphoinositide binding 2.2725849852584 bayes_pls_golite062009
binding 2.10831141109811 bayes_pls_golite062009
phospholipid binding 2.08170907241909 bayes_pls_golite062009
cholesterol binding 1.74311885098566 bayes_pls_golite062009
lipid binding 1.52883493550389 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle