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View Structure Prediction Details

Protein: SPP1
Organism: Saccharomyces cerevisiae
Length: 353 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPP1.

Description E-value Query
Range
Subject
Range
gi|76671142 - gi|76671142|ref|XP_877326.1| PREDICTED: similar to PHD finger protein 8 isoform 5 [Bos taurus]
167.0 [0..22] [205..5]
BAZ2B - bromodomain adjacent to zinc finger domain, 2B
gi|162319380 - gi|162319380|gb|AAI56488.1| Bromodomain adjacent to zinc finger domain, 2B [synthetic construct]
165.0 [0..23] [248..1932]
gi|74007017 - gi|74007017|ref|XP_549017.2| PREDICTED: similar to PHD finger protein 8 isoform 1 [Canis familiaris]
165.0 [0..22] [205..5]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPQWCPPH STLKRNPTTG EDVYCICKRP DYGELMVGCD GCDDWFHFTC LHIPEQFKDL  60
   61 VFSFYCPYCQ AGITGKNKDA IINGEGSLPK TLWKRKCRIS DCYKPCLQD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.0
Match: 1fp0A
Description: Nuclear corepressor KAP-1 (TIF-1beta)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [110-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKYCSEEHGR EFVNDIWSRL KTDEDRAVVK KMVEQTGHID KFKKFGQLDF IDNNIVVKTD  60
   61 DEKEIFDQIV VRDMTLKTLE DDLQEVQEIS LPLFKKKLEL LEVYLGWLDN VYTEMRKLDD 120
  121 DAASHVECGK EDSKGTKRKK KKNSSRSRAR KNICGYCSTY ERIPCSVEEF VRDFGSNEEA 180
  181 TKIHEVCTKW KC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.221849
Match: 1e6iA
Description: GCN5
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [302-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRHLDWVSTN QEQYLQQIDS LESMQERLQH LIQARKKQLN IQYYEEILRR GL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.739 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.739 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.715 a.4.1 Homeodomain-like
View Download 0.693 a.4.1 Homeodomain-like
View Download 0.681 a.4.1 Homeodomain-like
View Download 0.681 a.4.1 Homeodomain-like
View Download 0.636 a.4.1 Homeodomain-like
View Download 0.588 a.4.1 Homeodomain-like
View Download 0.574 a.4.5 "Winged helix" DNA-binding domain
View Download 0.563 a.60.1 SAM/Pointed domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle