YRC Public Data Repository - Protein Structure Prediction

Protein:	YPL113C
Organism:	Saccharomyces cerevisiae
Length:	396 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPL113C.

Description	E-value	Query Range	Subject Range
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	4.0E-88	[17..396]	[3..312]
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 /... SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus GN=serA PE=3 SV=1	2.0E-85	[16..396]	[1..312]
gi\|5771523, gi\|2... - gi\|5771523\|gb\|AAD51415.1\|AF171237_1 3-phosphoglycerate dehydrogenase [Homo sapiens], gi\|2674062\|gb\|A...	5.0E-84	[17..396]	[8..317]
gi\|19886634, gi\|... - gi\|20093737\|ref\|NP_613584.1\| D-3-phosphoglycerate dehydrogenase [Methanopyrus kandleri AV19], gi\|198...	6.0E-84	[17..396]	[3..313]
SERA_RAT - D-3-phosphoglycerate dehydrogenase OS=Rattus norvegicus GN=Phgdh PE=1 SV=3	1.0E-83	[17..396]	[8..317]
GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus GN=gyaR PE=3 SV=1 GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=gyaR ...	2.0E-82	[14..396]	[1..322]
gi\|14601656, gi\|... - gi\|5105521\|dbj\|BAA80834.1\| 347aa long hypothetical D-3-phosphoglycerate dehydrogenase [Aeropyrum per... gi\|7431353 - pir\|\|E72568 probable D-3-phosphoglycerate dehydrogenase APE1831 - Aeropyrum pernix (strain K1)	5.0E-82	[15..396]	[15..336]
GYAR_THELI - Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1 GYAR_THELN - Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=g...	6.0E-82	[14..396]	[1..322]
gi\|7431368 - gi\|7431368\|pir\|\|H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain... SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...	2.0E-81	[14..396]	[2..313]

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Predicted Domain #1

Region A:
Residues: [1-122]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITSIDIADV TYSAKPRILV PYKTQWEVAS HLPEYRKLAE RVEFYKYEMS TKDDFVKFLE  60
   61 THRINGFWLT EEFFTVLGNP SSYIEFFPAS LKVILVPWVG CDFIDGKLLR SKGITLCNIG 120
  121 PH

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [366-396]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VADMVIKQTL ITLENVQDIF VEGGDGKYVL N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	194.9794
Match:	1gdhA_
Description:	D-glycerate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [123-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AADHVTELAI FLAISCFRMT SFWEYCFKYV ENGNVEQCKK YISSDSYEIV TDSYHGQEMK  60
   61 FPSRTDKCKP NKDRKVVHLA EKYTVGGKKM ESPMNKKVLI LGFGSIGQNI GSNLHKVFNM 120
  121 SIEYYKRTGP VQKSLLDYNA KYHSDLDDPN TWKNADLIIL ALPSTASTNN IINRKSLAWC 180
  181 KDGVRIVNVG RGTCIDEDVL LDALESGKVA SCGLDVFKNE ETRVKQELLR RWDVTALPHI 240
  241 GST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	194.9794
Match:	1gdhA_
Description:	D-glycerate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits