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View Structure Prediction Details

Protein: PEX25
Organism: Saccharomyces cerevisiae
Length: 394 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX25.

Description E-value Query
Range
Subject
Range
PEX25 - Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenan...
gi|190407844 - gi|190407844|gb|EDV11109.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
PEX25_YEAST - Peroxisomal membrane protein PEX25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX25...
0.0 [1..394] [1..394]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQFGTTDIV SGSETPPYSG ASYQDAQDDN THPHSSDAGA EKFSAGSGSE SHTESSRSDD  60
   61 EDSQAKTKMV DNITILKYIL DSLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.535 a.77.1 DEATH domain
View Download 0.287 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.245 d.58.4 Dimeric alpha+beta barrel
View Download 0.240 d.58.17 Metal-binding domain
View Download 0.212 a.11.1 Acyl-CoA binding protein
View Download 0.202 a.156.1 S13-like H2TH domain

Predicted Domain #2
Region A:
Residues: [85-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRDKLAKIIK YALDILKLFI EKSKRNLTVL DPSVLTYYTK ILKNLTVKVA LRHPITVIKV  60
   61 LLLSLLRNFD KKIDFISQQL STFRYILRFG GTPFRVCSFL GKFNKTRKCN FQIDQIKKIW 120
  121 FNEASLREFL DLYYGIFDEL DLLYKLKIWT NKSFYSFVSR QESLAWQYDI LLSLKDHWLN 180
  181 LQSLQKRQLE LEVQLKVQNN ALLLSPILMH QAHKDDGSQS PIRKQLLNDL NVNNDAEVLI 240
  241 HKQLKAIKDE KTLVYLDIAR LSFDCMANTS DILNLKTPKG TYAVLSLGSG LTGLVKLWIT 300
  301 TKRSLCSSKD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.760 N/A N/A d.93.1 SH2 domain
View Download 0.748 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.743 N/A N/A d.50.1 dsRNA-binding domain-like
View Download 0.724 N/A N/A d.50.1 dsRNA-binding domain-like
View Download 0.690 N/A N/A d.129.1 TATA-box binding protein-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle