YRC Public Data Repository - Protein Structure Prediction

Protein:	YDC1
Organism:	Saccharomyces cerevisiae
Length:	317 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDC1.

Description	E-value	Query Range	Subject Range
gi\|190407868 - gi\|190407868\|gb\|EDV11133.1\| alkaline ceramidase YDC1 [Saccharomyces cerevisiae RM11-1a] YDC1 - Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroce... gi\|207340550 - gi\|207340550\|gb\|EDZ68866.1\| YPL087Wp-like protein [Saccharomyces cerevisiae AWRI1631] YDC1_YEAST - Alkaline ceramidase YDC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDC1 PE=1 SV=1 gi\|151942710 - gi\|151942710\|gb\|EDN61056.1\| alkaline dihydroceramidase [Saccharomyces cerevisiae YJM789]	0.0	[1..317]	[1..317]
gi\|157071806, gi... - gi\|164427589\|ref\|XP_965356.2\| hypothetical protein NCU02969 [Neurospora crassa OR74A], gi\|157071806\|... gi\|16945385 - gi\|16945385\|emb\|CAD11799.1\| conserved hypothetical protein [Neurospora crassa]	5.0E-80	[2..297]	[3..294]
ACER3_MOUSE - Alkaline ceramidase 3 OS=Mus musculus GN=Acer3 PE=2 SV=1	9.0E-79	[8..280]	[3..257]
ACER3 - alkaline ceramidase 3 gi\|114639456 - gi\|114639456\|ref\|XP_001175032.1\| PREDICTED: phytoceramidase, alkaline isoform 3 [Pan troglodytes]	2.0E-77	[8..282]	[3..259]
gi\|113549454, gi... - gi\|50917993\|ref\|XP_469393.1\| putative Acyl-CoA independent ceramide synthase [Oryza sativa (japonica...	1.0E-63	[9..282]	[3..248]
gi\|30793847, gi\|... - gi\|30794039\|gb\|AAP40465.1\| unknown protein [Arabidopsis thaliana], gi\|30793847\|gb\|AAP40376.1\| unknow...	2.0E-62	[12..289]	[5..254]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	7.0E-62	[24..289]	[148..385]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFSWPYPEA PIEGYWGKPT SLIDWCEENY VVSPYIAEWS NTITNSIFLM TAFYSTYSAW  60
   61 RNKLETRYIL IGMGFSLVGI GSWLFHMTLQ YRYQLLDELP MLYATIIPSW SIFAETQEIL 120
  121 IKDEKKRKES SFRIQMVISF IMCGIVTILT WIYVVVQKPA IFQVLYGILT LLVVVLSGWL 180
  181 TYYHVHDSFA KKNLFITMVM GMIPFVIGFI CWQLDIHLCS FWIYIRRTYL ALPLGVLLEL 240
  241 HAWWHLLTGT GVYIFVVYLQ YLRILTHGNP NDFLFIWRWG FFPELVRKGL PIGTSYSLEY 300
  301 LGPIVNTQVD DETKKNN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [86-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HMTLQYRYQL LDELPMLYAT IIPSWSIFAE TQEILIKDEK KRKESSFRIQ MVISFIMCGI  60
   61 VTILTWIYVV VQKPAIFQVL YGILTLLVVV LSGWLTYYHV HDSFAKKNLF ITMVMGMIPF 120
  121 VIGFICWQLD IHLCSFWIYI RRTYLALPLG VLLELHAWWH LLTGTGVYIF VVYLQYLRIL 180
  181 THGNPNDFLF IWRWGFFPEL VRKGLPIGTS YSLEYLGPIV NTQVDDETKK NN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.93
Match:	1f88A
Description:	Rhodopsin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits