YRC Public Data Repository - Protein Structure Prediction - Protein Overview

View Structure Prediction Details

Protein:	ERG10
Organism:	Saccharomyces cerevisiae
Length:	398 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERG10.

Description	E-value	Query Range	Subject Range
gi\|28202508, gi\|... - gi\|28210073\|ref\|NP_781017.1\| acetyl-CoA acetyltransferase [Clostridium tetani E88], gi\|28202508\|gb\|A...	0.0	[2..397]	[1..391]
THLA_CLOAB - Acetyl-CoA acetyltransferase OS=Clostridium acetobutylicum GN=thlA PE=1 SV=1 THLA_CLOAB - Acetyl-CoA acetyltransferase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / L...	0.0	[2..397]	[1..391]
gi\|170711812, gi... - gi\|170711812\|gb\|EDT23994.1\| acetyl-CoA acetyltransferase [Clostridium perfringens B str. ATCC 3626],... gi\|110799474, gi... - gi\|110799474\|ref\|YP_696874.1\| acetyl-CoA acetyltransferase [Clostridium perfringens ATCC 13124], gi\|... gi\|168213701, gi... - gi\|170714774\|gb\|EDT26956.1\| acetyl-CoA acetyltransferase [Clostridium perfringens CPE str. F4969], g... gi\|18145860, gi\|... - gi\|18311177\|ref\|NP_563111.1\| acetyl-CoA acetyltransferase [Clostridium perfringens str. 13], gi\|1814...	0.0	[2..397]	[1..392]
gi\|145013\|gb\|AAA... - 3-hydroxybutyric acid THIL_CHRVI - Acetyl-CoA acetyltransferase OS=Chromatium vinosum GN=phbA PE=3 SV=1	0.0	[1..397]	[1..393]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[2..397]	[1..392]
gi\|13622708, gi\|... - gi\|15675510\|ref\|NP_269684.1\| putative acetyl-CoA:acetyltransferase [Streptococcus pyogenes M1 GAS], ... gi\|71853939, gi\|... - gi\|71911157\|ref\|YP_282707.1\| acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS5005], gi\|7185...	0.0	[2..395]	[1..391]
gi\|20515538, gi\|... - gi\|20807050\|ref\|NP_622221.1\| acetyl-CoA acetyltransferase [Thermoanaerobacter tengcongensis MB4], gi... gi\|20807050 - gi\|20807050\|ref\|NP_622221.1\| acetyl-CoA acetyltransferase [Thermoanaerobacter tengcongensis MB4]	0.0	[2..396]	[1..393]
gi\|25286382 - pir\|\|E83903 thiolase (acetyl-CoA acetyltransferase) BH2029 [imported] - Bacillus halodurans (strain ... gi\|15614592, gi\|... - gi\|15614592\|ref\|NP_242895.1\| thiolase (acetyl-CoA acetyltransferase) [Bacillus halodurans C-125], gi...	0.0	[1..397]	[1..393]

Predicted Domain #1

Region A: Residues: [1-151]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MSQNVYIVST ARTPIGSFQG SLSSKTAVEL GAVALKGALA KVPELDASKD FDEIIFGNVL 60 61 SANLGQAPAR QVALAAGLSN HIVASTVNKV CASAMKAIIL GAQSIKCGNA DVVVAGGCES 120 121 MTNAPYYMPA ARAGAKFGQT VLVDGVERDG L [Run NCBI BLAST on this sequence.]
Region B: Residues: [198-222]	1 11 21 31 41 51 \| \| \| \| \| \| 1 FDNEIVPVTI KGFRGKPDTQ VTKDE [Run NCBI BLAST on this sequence.]
Region C: Residues: [254-282]	1 11 21 31 41 51 \| \| \| \| \| \| 1 INDGAAAVIL VSEKVLKEKN LKPLAIIKG [Run NCBI BLAST on this sequence.]
Region D: Residues: [353-368]	1 11 21 31 41 51 \| \| \| \| \| \| 1 GHPLGCSGAR VVVTLL [Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	861.457575
Match:	1dluA_
Description:	Biosynthetic thiolase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A: Residues: [152-197]	1 11 21 31 41 51 \| \| \| \| \| \| 1 NDAYDGLAMG VHAEKCARDW DITREQQDNF AIESYQKSQK SQKEGK [Run NCBI BLAST on this sequence.]
Region B: Residues: [223-253]	1 11 21 31 41 51 \| \| \| \| \| \| 1 EPARLHVEKL RSARTVFQKE NGTVTAANAS P [Run NCBI BLAST on this sequence.]
Region C: Residues: [283-352]	1 11 21 31 41 51 \| \| \| \| \| \| 1 WGEAAHQPAD FTWAPSLAVP KALKHAGIED INSVDYFEFN EAFSVVGLVN TKILKLDPSK 60 61 VNVYGGAVAL [Run NCBI BLAST on this sequence.]
Region D: Residues: [369-398]	1 11 21 31 41 51 \| \| \| \| \| \| 1 SILQQEGGKI GVAAICNGGG GASSIVIEKI [Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	861.457575
Match:	1dluA_
Description:	Biosynthetic thiolase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle