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View Structure Prediction Details

Protein: RRP12
Organism: Saccharomyces cerevisiae
Length: 1228 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[Show Ginzu Version Information]


Top Sequence Alignment Hits

No multiple sequence alignment data found for RRP12.

Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQDKVAFLL ELEDKLAKIR SQVNSKLENQ KHIAIILTAV EENIAGQATN DVSKNIVNYI  60
   61 ISFMSLLDQA VDPSTHEIKD IQLASSSTYL LDLIFHYSPK VLLRSKFSEI LTKIAPCITA 120
  121 EKANAPLIRA AIGCLESLLI AQDAQAWNNT YDLNVTPKRG LQGILELS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [169-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDVRPKVRKR ALDAVHAVLL NPPVAPTAEH VAAVFVADFC DKQLAGILND LSNLSNKQLK  60
   61 AQKTKEDINA SVMRSLRLIT SVVSTGQWPS SQIEPLCDVL LGVTKSSEQY LVSASFECFE 120
  121 SMFKTMAETT ISSGLAENKY LRVLDTIFAL KPSNVDTLLT KSWIAVVIKG MSTYATHQPL 180
  181 KALRKIPGVF HIMCTYLASE TPEVYQAASQ CLISILSESV KDDLLLYTPS V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [400-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEKVFKNVDE IISQIAKTFI DFLSIRYSHC SREILKILVA AFNKFRYRSN PHFLKSLKIV  60
   61 DTWRVNEEQF MDLRNEIELV IGASISAMGP EMILAEAPLN LDNPSSERP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [509-660]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRAWLLPLIR DYTKNANLAT FQNELAPYIK SFQSKFDKVP EESIQLRVFQ TIVDQIWSTL  60
   61 PRFCELPMDL RESFTDEFAS ELSSLLYSEV ELRTTICHAL KVLAESNVSY AEESSSHNVL 120
  121 LLQRFPISEA QKNIEYLSTK STNLLAVLFN VY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [661-733]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQTTPNARSY ILETIDQYLK ITSKEDLEKT FNNVCGLLKN SMNEESSGNV NKEKKKPQLT  60
   61 ATLLDLIICM ITY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [734-856]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPVSSYSALF SMFSLTVNSA DALIQKRAYR IITKLSELKS GSTAVAQFIS DIENVMVDSA  60
   61 SSVQTSAKAA RLTAIKTIVE LLPLDHLDFI VRTVAEVILS TKDVNEKSRE TAFDTLICMG 120
  121 RKM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [857-1065]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEPNGIIKLF QIPGYDPTTP DQSSSISEFF KIISAGLIGE SQHMVSSSIT GYACLVFEFK  60
   61 NELDSGILMD IYDTIELYLT SNSREIVKSA IGFTKVCVLG LPEELMRPKV PELLLKLLRW 120
  121 SHEHTGHFKA KVKHIIERLI RRFGYDYIEA NFPEEDRRLL TNIRKMRNRN KRKDEEVTTG 180
  181 VSDVAATKGS RFMSAFDEAV YGSDEENDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.045757
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1066-1228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSDQEENVAG GKMKNGAKQF IVESGDNPLD LLDSQTLAHI SSTRPKKFNK NQNRARFNDD  60
   61 AFNFDSEGKL VVKGQPKPST NVDDPLSAVT SGINAYLEAV KSGPVRGQRN KLKFRKNGKD 120
  121 SDEFGDDDDG EKDSRLMRGR VNQGNKIGKH NKKGPKFKSR KKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle