YRC Public Data Repository - Protein Structure Prediction

Protein:	RET3
Organism:	Saccharomyces cerevisiae
Length:	189 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RET3.

Description	E-value	Query Range	Subject Range
gi\|28949965 - gi\|28949965\|emb\|CAD70726.1\| probable clathrin assembly protein AP47 [Neurospora crassa]	6.0E-42	[8..184]	[1..166]
AP2M1_XENLA - AP-2 complex subunit mu OS=Xenopus laevis GN=ap2m1 PE=2 SV=1	7.0E-42	[8..184]	[1..169]
gi\|123987359, gi... - gi\|60655697\|gb\|AAX32412.1\| adaptor-related protein complex 2 mu 1 subunit [synthetic construct], gi\|... gi\|109042889, gi... - gi\|109042892\|ref\|XP_001102690.1\| PREDICTED: similar to adaptor-related protein complex 2, mu 1 subun... AP2M1 - adaptor-related protein complex 2, mu 1 subunit ENSCJAT00000025335 - null AP2M1_MOUSE - AP-2 complex subunit mu OS=Mus musculus GN=Ap2m1 PE=1 SV=1 gi\|114590717, gi... - gi\|114590719\|ref\|XP_001143649.1\| PREDICTED: adaptor-related protein complex 2, mu 1 subunit isoform ... gi\|149731154 - gi\|149731154\|ref\|XP_001497196.1\| PREDICTED: adaptor-related protein complex 2, mu 1 subunit isoform ... tr\|G1SM15\|G1SM15... - pep:novel chromosome:oryCun2:14:81523950:81532418:-1 gene:ENSOCUG00000004556 transcript:ENSOCUT00000... AP2M1_RAT - AP-2 complex subunit mu OS=Rattus norvegicus GN=Ap2m1 PE=1 SV=1 AP2M1_BOVIN - AP-2 complex subunit mu OS=Bos taurus GN=AP2M1 PE=2 SV=1 gi\|74003288, gi\|... - gi\|74003320\|ref\|XP_858515.1\| PREDICTED: similar to adaptor-related protein complex 2, mu 1 subunit i... AP2M1_MACFA - AP-2 complex subunit mu OS=Macaca fascicularis GN=AP2M1 PE=2 SV=1	2.0E-41	[8..184]	[1..169]
AP2MB_DANRE - AP-2 complex subunit mu-B OS=Danio rerio GN=ap2m1b PE=2 SV=1	2.0E-41	[8..184]	[1..169]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-41	[8..184]	[1..169]
gi\|119598696, gi... - gi\|68799814\|ref\|NP_001020376.1\| adaptor-related protein complex 2, mu 1 subunit isoform b [Homo sapi... gi\|74003298, gi\|... - gi\|74003324\|ref\|XP_858593.1\| PREDICTED: similar to adaptor-related protein complex 2, mu 1 subunit i... gi\|114590723, gi... - gi\|114590723\|ref\|XP_001144254.1\| PREDICTED: adaptor-related protein complex 2, mu 1 subunit isoform ... tr\|M3W8D5\|M3W8D5... - Adaptor related protein complex 2 mu 1 subunit OS=Felis catus GN=AP2M1 PE=3 SV=1 IPI:IPI00777075.... - Ensembl_locations(Chr-bp):11-5344589, Tax_Id=10116 Gene_Symbol=Ap2m1 49 kDa protein, Uncharacterized... gi\|148665155, gi... - gi\|74197238\|dbj\|BAE35162.1\| unnamed protein product [Mus musculus], gi\|148665155\|gb\|EDK97571.1\| adap... gi\|109042898, gi... - gi\|109042898\|ref\|XP_001102510.1\| PREDICTED: similar to adaptor-related protein complex 2, mu 1 subun... gi\|149731156 - gi\|149731156\|ref\|XP_001497163.1\| PREDICTED: adaptor-related protein complex 2, mu 1 subunit isoform ... gi\|76607427\|ref\|... - PREDICTED: similar to adaptor-related protein complex 2, mu 1 subunit isoform b isoform 1 [Bos tauru...	6.0E-41	[8..184]	[1..167]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSLYTVQ AVLILDQQGE RIYAKYYQPP HRSDEGHQLL FNSVKKQKEF EKQLYRKTHK  60
   61 QDSEILIFED HLVLYKEYID ITIYLVASLE ENEIVLQQGF SAIRGALDLI LNSGMDKKNI 120
  121 QENYDMVLLA IDETIDNGVI LETDSNTIAS RVSKPPTNEP QMALDLDKGF LGAWGFAKSK 180
  181 FQERLQQGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.221849
Match:	1gw5M_
Description:	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits