YRC Public Data Repository - Protein Structure Prediction

Protein:	RPS12
Organism:	Saccharomyces cerevisiae
Length:	143 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPS12.

Description	E-value	Query Range	Subject Range
gi\|219500954, gi... - gi\|219500954\|ref\|XP_002246877.1\| hypothetical protein BRAFLDRAFT_109012 [Branchiostoma floridae], gi... gi\|18845074 - gi\|18845074\|gb\|AAL79538.1\|AF470687_1 40S ribosomal protein S12 [Branchiostoma belcheri]	7.0E-39	[19..143]	[9..131]
RPS12 - ribosomal protein S12 tr\|G1SFR8\|G1SFR8... - pep:novel chromosome:oryCun2:12:123075000:123077422:1 gene:ENSOCUG00000001606 transcript:ENSOCUT0000... gi\|1085435 - pir\|\|JC4159 ribosomal protein S12 - pig RS12_BOVIN - 40S ribosomal protein S12 OS=Bos taurus GN=RPS12 PE=2 SV=1 RS12_PIG - 40S ribosomal protein S12 OS=Sus scrofa GN=RPS12 PE=2 SV=2 gi\|149032886, gi... - gi\|78126139\|ref\|NP_113897.2\| ribosomal protein S12 [Rattus norvegicus], gi\|34849622\|gb\|AAH58460.1\| R... gi\|55627400 - gi\|55627400\|ref\|XP_518748.1\| PREDICTED: similar to ribosomal protein S12 [Pan troglodytes] gi\|40254577 - ref\|NP_035425.2\| ribosomal protein S12 [Mus musculus] ENSCJAT00000005492 - null gi\|109082720, gi... - gi\|109082724\|ref\|XP_001094552.1\| PREDICTED: similar to ribosomal protein S12 isoform 3 [Macaca mulat... gi\|126310576 - gi\|126310576\|ref\|XP_001369942.1\| PREDICTED: similar to 40S ribosomal protein S12 [Monodelphis domest... gi\|149722961 - gi\|149722961\|ref\|XP_001504406.1\| PREDICTED: ribosomal protein S12 [Equus caballus] gi\|61363690, gi\|... - gi\|61363697\|gb\|AAX42430.1\| ribosomal protein S12 [synthetic construct], gi\|61363690\|gb\|AAX42429.1\| r... gi\|74141830, gi\|... - gi\|94406873\|ref\|XP_992944.1\| PREDICTED: similar to ribosomal protein S12 [Mus musculus], gi\|94382274... gi\|73945533, gi\|... - gi\|73945535\|ref\|XP_859516.1\| PREDICTED: similar to ribosomal protein S12 isoform 7 [Canis familiaris...	2.0E-38	[16..143]	[6..131]
gi\|148231845, gi... - gi\|27881763\|gb\|AAH44028.1\| Rps12-prov protein [Xenopus laevis], gi\|148231845\|ref\|NP_001080594.1\| rib... gi\|51258906, gi\|... - gi\|89272933\|emb\|CAJ82890.1\| ribosomal protein S12 [Xenopus tropicalis], gi\|56605872\|ref\|NP_001008435...	3.0E-38	[18..143]	[8..131]
gi\|28566194 - gi\|28566194\|gb\|AAO43049.1\| 40S ribosomal protein [Perinereis aibuhitensis]	5.0E-38	[1..143]	[1..137]
gi\|71681449, gi\|... - gi\|94389552\|ref\|XP_979295.1\| PREDICTED: similar to ribosomal protein S12 [Mus musculus], gi\|83028004...	2.0E-36	[16..143]	[6..131]
RS12_ORENI - 40S ribosomal protein S12 OS=Oreochromis niloticus GN=rps12 PE=2 SV=3	3.0E-36	[18..143]	[8..131]
gi\|27717927, gi\|... - gi\|27717927\|ref\|XP_235021.1\| PREDICTED: similar to ribosomal protein S12 [Rattus norvegicus], gi\|157...	8.0E-36	[16..143]	[6..131]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDVEEVVEV QEETVVEQTA EVTIEDALKV VLRTALVHDG LARGLRESTK ALTRGEALLV  60
   61 VLVSSVTEAN IIKLVEGLAN DPENKVPLIK VADAKQLGEW AGLGKIDREG NARKVVGASV 120
  121 VVVKNWGAET DELSMIMEHF SQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.69897
Match:	1e7kA_
Description:	Spliceosomal 15.5kd protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	7.52323416912124	bayes_pls_golite062009
structural molecule activity	6.97581143389173	bayes_pls_golite062009
RNA binding	3.17103797166833	bayes_pls_golite062009
nucleic acid binding	1.89156659324072	bayes_pls_golite062009
binding	1.31970199852267	bayes_pls_golite062009
	0.61812240381857	bayes_pls_golite062009
catalytic activity	0.264002643439785	bayes_pls_golite062009
mRNA binding	0.259807967594031	bayes_pls_golite062009
protein binding	0.128962984939985	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: